A Radiomics Approach With CNN for Shear-Wave Elastography Breast Tumor Classification.

Journal: IEEE transactions on bio-medical engineering
Published Date:

Abstract

This paper proposes a segmentation-free radiomics method to classify malignant and benign breast tumors with shear-wave elastography (SWE) data. The method is targeted to integrate the advantage of both SWE in providing important elastic with morphology information and convolutional neural network (CNN) in automatic feature extraction and accurate classification. Compared to traditional methods, the proposed method is designed to directly extract features from the dataset without the prerequisite of segmentation and manual operation. This can keep the peri-tumor information, which is lost by segmentation-based methods. With the proposed model trained on 540 images (318 of malignant breast tumors and 222 of benign breast tumors, respectively), an accuracy of 95.8%, a sensitivity of 96.2%, and a specificity of 95.7% was obtained for the final test. The superior performances compared to the existing state-of-the-art methods and its automatic nature both demonstrate that the proposed method has a great potential to be applied to clinical computer-aided diagnosis of breast cancer.

Authors

  • Yongjin Zhou
  • Jingxu Xu
    Department of Research Collaboration, R&D Center, Beijing Deepwise & League of PHD Technology Co., Ltd., Beijing, China.
  • Qiegen Liu
    Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Shenzhen, Guangdong, China.
  • Cheng Li
    College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
  • Zaiyi Liu
    Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
  • Meiyun Wang
  • Hairong Zheng
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Shanshan Wang
    Key Laboratory of Agri-food Safety and Quality, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Ministry of Agriculture of China, Beijing, 100081, PR China.