3D freehand ultrasound without external tracking using deep learning.

Journal: Medical image analysis
Published Date:

Abstract

This work aims at creating 3D freehand ultrasound reconstructions from 2D probes with image-based tracking, therefore not requiring expensive or cumbersome external tracking hardware. Existing model-based approaches such as speckle decorrelation only partially capture the underlying complexity of ultrasound image formation, thus producing reconstruction accuracies incompatible with current clinical requirements. Here, we introduce an alternative approach that relies on a statistical analysis rather than physical models, and use a convolutional neural network (CNN) to directly estimate the motion of successive ultrasound frames in an end-to-end fashion. We demonstrate how this technique is related to prior approaches, and derive how to further improve its predictive capabilities by incorporating additional information such as data from inertial measurement units (IMU). This novel method is thoroughly evaluated and analyzed on a dataset of 800 in vivo ultrasound sweeps, yielding unprecedentedly accurate reconstructions with a median normalized drift of 5.2%. Even on long sweeps exceeding 20 cm with complex trajectories, this allows to obtain length measurements with median errors of 3.4%, hence paving the way toward translation into clinical routine.

Authors

  • Raphael Prevost
    ImFusion GmbH, Agnes-Pockels-Bogen 1, Munich, Germany. Electronic address: prevost@imfusion.de.
  • Mehrdad Salehi
    ImFusion GmbH, Agnes-Pockels-Bogen 1, Munich, Germany; Computer Aided Medical Procedures (CAMP), TU Munich, Munich, Germany.
  • Simon Jagoda
    ImFusion GmbH, Agnes-Pockels-Bogen 1, Munich, Germany.
  • Navneet Kumar
    ImFusion GmbH, Agnes-Pockels-Bogen 1, Munich, Germany.
  • Julian Sprung
    Piur Imaging GmbH, Vienna, Austria.
  • Alexander Ladikos
    ImFusion GmbH, Agnes-Pockels-Bogen 1, Munich, Germany.
  • Robert Bauer
    Division of Translational Neurosurgery & Division of Functional and Restorative Neurosurgery, Department of Neurosurgery, and Centre for Integrative Neuroscience, University of Tuebingen, Germany. Electronic address: robert.bauer@cin.uni-tuebingen.de.
  • Oliver Zettinig
    Computer Aided Medical Procedures, Technische Universität München, Munich, Germany.
  • Wolfgang Wein
    ImFusion GmbH, Agnes-Pockels-Bogen 1, Munich, Germany.