Towards the Establishment of a Biomedical Ontology for the Primary Sjögren's Syndrome.

Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Published Date: Jul 1, 2018

Abstract

Primary Sjögren's Syndrome (pSS) has been characterized as a hypersensitivity reaction type II systemic autoimmune chronic disease causing exocrine gland dysfunction mainly affecting women near the menopausal age. pSS patients exhibit dryness of the main mucosal surfaces and are highly prone to lymphoma development. This paper presents a first biomedical ontology for pSS based on a reference model which was determined by pSS clinical experts. The ensuing ontology constitutes the fundamental basis for mapping pSS-related ontologies from international cohorts to a common ontology. The ontology mapping (i.e., schematic interlinking) procedure is, in fact, a preliminary step to harmonize heterogeneous medical data obtained from various cohorts.

Authors

  • Vasileios C Pezoulas
    Unit of Medical Technology and Intelligent Information Systems, Dept. of Material Science and Engineering, University of Ioannina, GR45110, Ioannina, Greece.
  • Themis P Exarchos
    Institute of Communication and Computer Systems, National Technical University of Athens, Athens, Greece, Themis.exarchos@gmail.com.
  • Vassiliki Andronikou
  • Theodora Varvarigou
  • Athanasios G Tzioufas
    Department of Pathophysiology and Joint Rheumatology, Medical School, National and Kapodistrian University of Athens, Greece; Biomedical Research Foundation of the Academy of Athens, Greece; Research Institute for Systemic Autoimmune Diseases, Greece.
  • Salvatore De Vita
  • Dimitrios I Fotiadis
    Biomedical Research Institute, Foundation for Research and Technology Hellas, Greece; Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Greece.

Keywords

External Resources

Popular Topics
Recent Journals