Diagnosis of Heart Failure With Preserved Ejection Fraction: Machine Learning of Spatiotemporal Variations in Left Ventricular Deformation.

Journal: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
PMID: 30146187

Abstract

BACKGROUND: Stress testing helps diagnose heart failure with preserved ejection fraction (HFpEF), but there are no established criteria for quantifying left ventricular (LV) functional reserve. The aim of this study was to investigate whether comprehensive analysis of the timing and amplitude of LV long-axis myocardial motion and deformation throughout the cardiac cycle during rest and stress can provide more informative criteria than standard measurements.

Authors

  • Mahdi Tabassian
    Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium. mahdi.tabassian@kuleuven.be.
  • Imran Sunderji
    Wales Heart Research Institute, Cardiff University, Cardiff, United Kingdom.
  • Tamas Erdei
    Wales Heart Research Institute, Cardiff University, United Kingdom.
  • Sergio Sanchez-Martinez
    Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain. Electronic address: sergio.sanchezm@upf.edu.
  • Anna Degiovanni
    Department of Thoracic, Heart and Vascular Diseases, Maggiore Della Carità Hospital, Corso Mazzini 18, 28100 Novara, Italy.
  • Paolo Marino
    Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain (S.S.-M., G.P., B.H.B.); Asclepios Research Group, Université Côte d'Azur, Inria, Sophia Antipolis, France (N.D.); Wales Heart Research Institute, Cardiff University, United Kingdom (T.E., A.G.F.); Department of Cardiology, Oslo University Hospital, Norway (G.K., S.A.); Department of Circulation and Imaging, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway (S.A.); Clinic of Cardiology, St. Olav Hospital, Trondheim, Norway (S.A.); Department of Cardiology, University of Eastern Piedmont, Novara, Italy (A.D., P.M.); Division of Cardiology, University Hospital "S.Maria della Misericordia", Perugia, Italy (E.C.); and Catalan Institution for Research and Advanced Studies, Barcelona, Spain (B.H.B.).
  • Alan G Fraser
    Wales Heart Research Institute, Cardiff University Cardiff UK.
  • Jan D'hooge
    Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.

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