AIMC Topic: Heart Failure

Clear Filters Showing 1 to 10 of 446 articles

Toward developing a compact total artificial heart using a soft robotic fluidic transmission system.

Science advances Jul 2, 2025
Cardiovascular diseases are a leading cause of mortality, with limited possibilities for transplantation due to a critical shortage of donor hearts. Replacing the heart with total artificial hearts (TAHs) remains challenging, due to size constraints ...
Robotics Equipment Design Heart Failure Heart, Artificial Humans
View on PubMed DOI

Integrating bioinformatics and machine learning to investigate the mechanisms by which three major respiratory infectious diseases exacerbate heart failure.

Scientific reports Jul 2, 2025
Heart failure (HF) is a severe cardiovascular disease often worsened by respiratory infections like influenza, COVID-19, and community-acquired pneumonia (CAP). This study aims to uncover the molecular commonalities among these respiratory diseases a...
Gene Regulatory Networks Computational Biology Humans Heart Failure Influenza, Human Machine Learning Community-Acquired Infections COVID-19 SARS-CoV-2 ROC Curve
View on PubMed DOI

Machine learning methods, applications and economic analysis to predict heart failure hospitalisation risk: a scoping review.

BMJ open Jun 25, 2025
BACKGROUND:  Machine Learning (ML) has been transformative in healthcare, enabling more precise diagnostics, personalised treatment regimens and enhanced patient care. In cardiology, ML plays a crucial role in risk prediction and patient stratificati...
Machine Learning Hospitalization Risk Assessment Humans Heart Failure Patient Readmission
View on PubMed DOI

Optimization of hemocompatibility metrics in ventricular assist device design using machine learning and CFD-based response surface analysis.

The International journal of artificial organs Jun 6, 2025
Ventricular assist devices (VADs) are essential for end-stage heart failure patients, but their design must balance hydraulic efficiency and hemocompatibility to minimize blood damage. This study presents a multi-objective optimization framework inte...
Stress, Mechanical Hemolysis Hydrodynamics Models, Cardiovascular Platelet Activation Heart Failure Materials Testing Heart-Assist Devices Computer Simulation Bayes Theorem Prosthesis Design Humans Machine Learning
View on PubMed DOI

Epistasis regulates genetic control of cardiac hypertrophy.

Nature cardiovascular research Jun 5, 2025
Although genetic variant effects often interact nonadditively, strategies to uncover epistasis remain in their infancy. Here we develop low-signal signed iterative random forests to elucidate the complex genetic architecture of cardiac hypertrophy, u...
Male Middle Aged Deep Learning Phenotype Female Aged Magnetic Resonance Imaging Receptor, IGF Type 1 Heart Failure Ventricular Remodeling Genome-Wide Association Study Gene Regulatory Networks Genetic Predisposition to Disease Humans Induced Pluripotent Stem Cells Connectin Myocytes, Cardiac Hypertrophy, Left Ventricular Epistasis, Genetic
View on PubMed DOI

A soft robotic total artificial hybrid heart.

Nature communications Jun 3, 2025
End-stage heart failure is a deadly disease. Current total artificial hearts (TAHs) carry high mortality and morbidity and offer low quality of life. To overcome current biocompatibility issues, we propose the concept of a soft robotic, hybrid (pumpi...
Animals Male Rats Biocompatible Materials Robotics Humans Heart, Artificial Tissue Engineering Goats Heart Failure
View on PubMed DOI

Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos.

Circulation research May 22, 2025
Over the past few decades, the rising burden of metabolic disease, including type 2 diabetes, prediabetes, obesity, and metabolic dysfunction-associated steatotic liver disease, has corresponded with fundamental shifts in the landscape of heart failu...
Humans Animals Kidney Liver Heart Failure
View on PubMed DOI

Identification of m5C RNA modification-related gene signature for predicting prognosis and immune microenvironment-related characteristics of heart failure.

Hereditas May 22, 2025
BACKGROUND: Methylation of RNA is involved in many pathophysiological processes. The roles of N6-methyladenosine (m6A) and N7-methylguanosine (m7G) in heart failure (HF) have been established. However, the impact of 5-methylcytosine (m5C) on HF and i...
Prognosis Animals Humans Rats Heart Failure Gene Expression Profiling 5-Methylcytosine Transcriptome Gene Regulatory Networks
View on PubMed DOI

Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes.

Journal of translational medicine May 15, 2025
BACKGROUND: Limited access to echocardiography can delay the diagnosis of suspected heart failure (HF), which in turn postpones the initiation of optimal guideline-directed medical therapy. Although natriuretic peptides like B-type natriuretic peptid...
Proteomics Heart Failure Early Diagnosis Natriuretic Peptide, Brain Male Middle Aged Cohort Studies Biomarkers Female Aged Humans
View on PubMed DOI

Multimodal Visualization and Explainable Machine Learning-Driven Markers Enable Early Identification and Prognosis Prediction for Symptomatic Aortic Stenosis and Heart Failure With Preserved Ejection Fraction After Transcatheter Aortic Valve Replacement: Multicenter Cohort Study.

Journal of medical Internet research May 1, 2025
BACKGROUND: Currently, there is a paucity of literature addressing personalized risk stratification using multimodal data in patients with symptomatic aortic stenosis and heart failure with preserved ejection fraction (HFpEF) following transcatheter ...
Heart Failure Transcatheter Aortic Valve Replacement Aged, 80 and over Prognosis Humans Risk Assessment Male Female Machine Learning Stroke Volume Cohort Studies Aged Biomarkers Aortic Valve Stenosis
View on PubMed DOI
Popular Topics
Recent Journals