Global firing rate contrast enhancement in E/I neuronal networks by recurrent synchronized inhibition.

Journal: Chaos (Woodbury, N.Y.)
Published Date:

Abstract

Inhibitory synchronization is commonly observed and may play some important functional roles in excitatory/inhibitory (E/I) neuronal networks. The firing rate contrast enhancement is a general feature of information processing in sensory pathways, and a new mechanism of contrast enhancement by inhibitory synchronization in E/I neuronal networks is investigated in this paper. Inspired by the firing rate contrast enhancement phenomenon by the lateral feed-forward inhibition, we reveal that the firing rate contrast enhancement could also occur by recurrent inhibition in E/I networks. It is further found that the synchronized inhibitory neurons act as a global inhibition which can enhance the firing rate contrast of excitatory neurons globally in synchronized E/I networks, even in partially synchronous states. Therefore, the firing rate contrast enhancement might be an important function of inhibitory synchronization and might facilitate information transmission in neural systems.

Authors

  • Fang Han
    Department of Respiratory Medicine and Intensive Care Unit.Peking University People's Hospital, Beijing 100044, China; Email: hanfangl@hotmail.com.
  • Xiaochun Gu
    College of Information Science and Technology, Donghua University, Shanghai 201620, People's Republic of China.
  • Zhijie Wang
    GE Health Care, London, Ontario, Canada. Electronic address: zhijie@ualberta.ca.
  • Hong Fan
    Glorious Sun School of Business and Management, Donghua University, Shanghai 200051, People's Republic of China.
  • Jinfeng Cao
    College of Information Science and Technology, Donghua University, Shanghai 201620, People's Republic of China.
  • Qishao Lu
    School of Science, Beihang University, Beijing 100191, People's Republic of China.