Predicting adverse drug reactions through interpretable deep learning framework.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: Adverse drug reactions (ADRs) are unintended and harmful reactions caused by normal uses of drugs. Predicting and preventing ADRs in the early stage of the drug development pipeline can help to enhance drug safety and reduce financial costs.

Authors

  • Sanjoy Dey
    Center for Computational Health, IBM Research, Yorktown Heights, NY, USA.
  • Heng Luo
    Center for Computational Health, IBM T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY, USA.
  • Achille Fokoue
    Cognitive Computing, IBM T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY, USA.
  • Jianying Hu
    Center for Computational Health, IBM Research, Yorktown Heights, NY, USA.
  • Ping Zhang
    Department of Computer Science and Engineering, The Ohio State University, USA.