Resting state connectivity best predicts alcohol use severity in moderate to heavy alcohol users.

Journal: NeuroImage. Clinical
Published Date: Mar 19, 2019

Abstract

BACKGROUND: In the United States, 13% of adults are estimated to have alcohol use disorder (AUD). Most studies examining the neurobiology of AUD treat individuals with this disorder as a homogeneous group; however, the theories of the neurocircuitry of AUD call for a quantitative and dimensional approach. Previous imaging studies find differences in brain structure, function, and resting-state connectivity in AUD, but few use a multimodal approach to understand the association between severity of alcohol use and the brain differences.

Authors

  • Samantha J Fede
    Clinical NeuroImaging Research Core, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20814, MSC 1108, United States. Electronic address: fedesj@nih.gov.
  • Erica N Grodin
    Clinical NeuroImaging Research Core, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20814, MSC 1108, United States.
  • Sarah F Dean
    Clinical NeuroImaging Research Core, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20814, MSC 1108, United States.
  • Nancy Diazgranados
    Office of Clinical Director, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20814, MSC 1108, United States.
  • Reza Momenan
    Clinical NeuroImaging Research Core, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20814, MSC 1108, United States. Electronic address: rezam@nih.gov.

Keywords

External Resources

Popular Topics
Recent Journals