The use of natural language processing to identify Tdap-related local reactions at five health care systems in the Vaccine Safety Datalink.

Journal: International journal of medical informatics
PMID: 31128829

Abstract

OBJECTIVE: Local reactions are the most common vaccine-related adverse event. There is no specific diagnosis code for local reaction due to vaccination. Previous vaccine safety studies used non-specific diagnosis codes to identify potential local reaction cases and confirmed the cases through manual chart review. In this study, a natural language processing (NLP) algorithm was developed to identify local reaction associated with tetanus-diphtheria-acellular pertussis (Tdap) vaccine in the Vaccine Safety Datalink.

Authors

  • Chengyi Zheng
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California. Electronic address: Chengyi.X.Zheng@kp.org.
  • Wei Yu
    Quality Control Department, Jiangxi Provincial Blood Center Nanchang 330052, Jiangxi, China.
  • Fagen Xie
    Kaiser Permanente Southern California, Pasadena, CA, USA.
  • Wansu Chen
    Kaiser Permanente Southern California, Pasadena, CA, USA.
  • Cheryl Mercado
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
  • Lina S Sy
    Kaiser Permanente Southern California, Pasadena, CA, USA.
  • Lei Qian
    Kaiser Permanente Southern California, Pasadena, CA, USA.
  • Sungching Glenn
    Kaiser Permanente Southern California, Pasadena, CA, USA.
  • Gina Lee
    Kaiser Permanente Southern California, Pasadena, CA, USA.
  • Hung Fu Tseng
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
  • Jonathan Duffy
    Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Lisa A Jackson
    Kaiser Permanente Washington Health Research Institute, Seattle, WA, United States. Electronic address: Jackson.L@ghc.org.
  • Matthew F Daley
    Kaiser Permanente Colorado, Denver, CO, USA.
  • Brad Crane
    Kaiser Permanente Northwest, Portland, OR, USA.
  • Huong Q McLean
    Marshfield Clinic Research Institute, Marshfield, WI, USA.
  • Steven J Jacobsen
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.

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