AIMC Topic: Vaccination

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Effects of a Theory- and Evidence-Based, Motivational Interviewing-Oriented Artificial Intelligence Digital Assistant on Vaccine Attitudes: A Randomized Controlled Trial.

Journal of medical Internet research
BACKGROUND: Attitude-targeted interventions are important approaches for promoting vaccination. Educational approaches alone cannot effectively cultivate positive vaccine attitudes. Artificial intelligence (AI)-driven chatbots and motivational interv...

Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis.

Human vaccines & immunotherapeutics
Exploring the influencing factors of COVID-19 vaccine hesitancy and summarizing countermeasures is of great significance for effectively addressing potential public health crises. Based on survey data from China, we employed a Gradient Boosting Decis...

Prediction and characterisation of the human B cell response to a heterologous two-dose Ebola vaccine.

Nature communications
Ebola virus disease (EVD) outbreaks are increasing, posing significant threats to affected communities. Effective outbreak management depends on protecting frontline health workers, a key focus of EVD vaccination strategies. IgG specific to the viral...

Ethical Implications of Artificial Intelligence in Vaccine Equity: Protocol for Exploring Vaccine Distribution Planning and Scheduling in Pandemics in Low- and Middle-Income Countries.

JMIR research protocols
BACKGROUND: The COVID-19 pandemic highlighted significant disparities in vaccine distribution, particularly in low- and middle-income countries (LMICs). Artificial intelligence (AI) has emerged as a potential tool to optimize vaccine distribution pla...

Leveraging pre-vaccination antibody titres across multiple influenza H3N2 variants to forecast the post-vaccination response.

EBioMedicine
BACKGROUND: Despite decades of research on the influenza virus, we still lack a predictive understanding of how vaccination reshapes each person's antibody response, which impedes efforts to design better vaccines. Models using pre-vaccination antibo...

Anti-HBs persistence and anamnestic response among medical interns vaccinated in infancy.

Scientific reports
Medical interns are at high risk of acquiring Hepatitis B Virus (HBV) infection during their training. HBV vaccination is the most effective measure to reduce the global incidence of HBV. The duration of protection after HBV vaccination is still cont...

A vaccine chatbot intervention for parents to improve HPV vaccination uptake among middle school girls: a cluster randomized trial.

Nature medicine
Conversational artificial intelligence, in the form of chatbots powered by large language models, offers a new approach to facilitating human-like interactions, yet its efficacy in enhancing vaccination uptake remains under-investigated. This study a...

Modifiable risk factors of vaccine hesitancy: insights from a mixed methods multiple population study combining machine learning and thematic analysis during the COVID-19 pandemic.

BMC medicine
BACKGROUND: Vaccine hesitancy, the delay in acceptance or reluctance to vaccinate, ranks among the top threats to global health. Identifying modifiable factors contributing to vaccine hesitancy is crucial for developing targeted interventions to incr...

Unraveling the power of NAP-CNB's machine learning-enhanced tumor neoantigen prediction.

eLife
In this study, we present a proof-of-concept classical vaccination experiment that validates the in silico identification of tumor neoantigens (TNAs) using a machine learning-based platform called NAP-CNB. Unlike other TNA predictors, NAP-CNB leverag...