AIMC Topic: Vaccination

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A data-driven machine learning framework to predict side effects of AstraZeneca and sinopharm COVID-19 vaccines.

Scientific reports
Due to the widespread COVID-19 vaccinations, we are focusing more on side effects to immunizations that might affect people's perceptions, and ultimately vaccine hesitancy. Machine learning (ML)-based predictive models using individual-level data ser...

Innovations and challenges in vaccine development: Lessons from the SARS-CoV-2 pandemic and prospects.

Biochemical and biophysical research communications
Vaccination stands as one of the most significant achievements in public health, dramatically reducing the incidence of infectious diseases worldwide. The COVID-19 pandemic has catalyzed revolutionary advancements in vaccinology, particularly through...

Mapping inequities in global vaccine sentiment research.

BMJ global health
INTRODUCTION: Negative public sentiment towards vaccination (PSV) poses significant challenges to the effectiveness of immunisation programmes, with dramatic effects on morbidity and mortality for vaccine-preventable diseases. Yet, health research is...

Vaccination at a crossroad: science, politics and public trust.

Swiss medical weekly
Vaccine hesitancy threatens to erode one of medicine's greatest achievements. Recent measles outbreaks in Europe and the United States illustrate the consequences of declining confidence. At the centre lies misinformation, amplified through digital n...

Predictors of childhood vaccination uptake in England: an explainable machine learning analysis of regional data (2021-2024).

Vaccine
BACKGROUND: Childhood vaccination is a cornerstone of public health, yet disparities in vaccination coverage persist across England. These disparities arise from complex interactions among geographic, demographic, socioeconomic, and cultural (GDSC) f...

Invasive meningococcal disease in adolescents in Europe and select geographies: Disease burden, unmet medical need, and optimizing prevention.

Human vaccines & immunotherapeutics
Invasive meningococcal disease (IMD) is uncommon but serious; the case fatality rate is 8-15% and up to 20-40% of survivors experience disabling sequelae, with a substantial socioeconomic impact. Although incidence is highest in infants and young chi...

Drivers of herpes zoster vaccine hesitancy in adults aged 50 and above: A machine learning approach.

Vaccine
BACKGROUND: Herpes zoster (HZ) poses a growing public health challenge among adults aged 50 and above, with vaccine hesitancy being a major barrier to improving immunization rates. Understanding the factors driving HZ vaccine hesitancy is essential f...

Using machine learning models to predict vaccine hesitancy: a showcase of COVID-19 vaccine hesitancy in rural populations during the pandemic.

Vaccine
Understanding vaccine hesitancy is a critical public health challenge, yet traditional statistical methods often fail to capture the complex drivers behind it. This study uses COVID-19 vaccine hesitancy in a rural population as a case study to demons...

Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination.

Gut microbes
Vaccines are one of the most significant achievements in global health, as they have substantially reduced morbidity and mortality from infectious diseases. However, the vaccine efficacy varies markedly across different populations, particularly amon...