Deep Attentive Features for Prostate Segmentation in 3D Transrectal Ultrasound.

Journal: IEEE transactions on medical imaging
Published Date:

Abstract

Automatic prostate segmentation in transrectal ultrasound (TRUS) images is of essential importance for image-guided prostate interventions and treatment planning. However, developing such automatic solutions remains very challenging due to the missing/ambiguous boundary and inhomogeneous intensity distribution of the prostate in TRUS, as well as the large variability in prostate shapes. This paper develops a novel 3D deep neural network equipped with attention modules for better prostate segmentation in TRUS by fully exploiting the complementary information encoded in different layers of the convolutional neural network (CNN). Our attention module utilizes the attention mechanism to selectively leverage the multi-level features integrated from different layers to refine the features at each individual layer, suppressing the non-prostate noise at shallow layers of the CNN and increasing more prostate details into features at deep layers. Experimental results on challenging 3D TRUS volumes show that our method attains satisfactory segmentation performance. The proposed attention mechanism is a general strategy to aggregate multi-level deep features and has the potential to be used for other medical image segmentation tasks. The code is publicly available at https://github.com/wulalago/DAF3D.

Authors

  • Yi Wang
    Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
  • Haoran Dou
    National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University, Shenzhen, 518060, China.
  • Xiaowei Hu
    Dept. of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong, China.
  • Lei Zhu
    School of Civil and Hydraulic Engineering, Ningxia University, Yinchuan, China.
  • Xin Yang
    Department of Oral Maxillofacial-Head Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
  • Ming Xu
    Shenyang Analytical Application Center, Shimadzu (China) Co. Ltd., Shenyang, 167 Qingnian Street, Shenyang, 110016, PR China.
  • Jing Qin
    School of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
  • Pheng-Ann Heng
  • Tianfu Wang
    School of Biomedical Engineering, Shenzhen University Health Sciences Center, Shenzhen, Guangdong 518060, P.R.China.
  • Dong Ni