Differentiating post-cancer from healthy tongue muscle coordination patterns during speech using deep learning.

Journal: The Journal of the Acoustical Society of America
Published Date:

Abstract

The ability to differentiate post-cancer from healthy tongue muscle coordination patterns is necessary for the advancement of speech motor control theories and for the development of therapeutic and rehabilitative strategies. A deep learning approach is presented to classify two groups using muscle coordination patterns from magnetic resonance imaging (MRI). The proposed method uses tagged-MRI to track the tongue's internal tissue points and atlas-driven non-negative matrix factorization to reduce the dimensionality of the deformation fields. A convolutional neural network is applied to the classification task yielding an accuracy of 96.90%, offering the potential to the development of therapeutic or rehabilitative strategies in speech-related disorders.

Authors

  • Jonghye Woo
    Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Fangxu Xing
    Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Jerry L Prince
    Department of Electrical and Computer Engineering, The Johns Hopkins University, United States.
  • Maureen Stone
    Department of Neural and Pain Sciences, University of Maryland School of Dentistry, Baltimore, MD, USA.
  • Jordan R Green
    e Department of Communication Sciences and Disorders , MGH Institute of Health Professions , Boston , MA , USA.
  • Tessa Goldsmith
    Department of Speech, Language and Swallowing Disorders, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
  • Timothy G Reese
    Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USAjwoo@mgh.harvard.edu, fxing1@mgh.harvard.edu, prince@jhu.edu, mstone@umaryland.edu, jgreen2@mghihp.edu, tgoldsmith@partners.org, reese@nmr.mgh.harvard.edu, van@nmr.mgh.harvard.edu, elfakhri.georges@mgh.harvard.edu.
  • Van J Wedeen
    Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USAjwoo@mgh.harvard.edu, fxing1@mgh.harvard.edu, prince@jhu.edu, mstone@umaryland.edu, jgreen2@mghihp.edu, tgoldsmith@partners.org, reese@nmr.mgh.harvard.edu, van@nmr.mgh.harvard.edu, elfakhri.georges@mgh.harvard.edu.
  • Georges El Fakhri