On the interpretability of machine learning-based model for predicting hypertension.

Journal: BMC medical informatics and decision making
PMID:

Abstract

BACKGROUND: Although complex machine learning models are commonly outperforming the traditional simple interpretable models, clinicians find it hard to understand and trust these complex models due to the lack of intuition and explanation of their predictions. The aim of this study to demonstrate the utility of various model-agnostic explanation techniques of machine learning models with a case study for analyzing the outcomes of the machine learning random forest model for predicting the individuals at risk of developing hypertension based on cardiorespiratory fitness data.

Authors

  • Radwa Elshawi
    Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Mouaz H Al-Mallah
    Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, Michigan; King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King AbdulAziz Cardiac Center, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia. Electronic address: mouaz74@gmail.com.
  • Sherif Sakr
    King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King AbdulAziz Cardiac Center, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia.