Precise estimation of renal vascular dominant regions using spatially aware fully convolutional networks, tensor-cut and Voronoi diagrams.

Journal: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Published Date:

Abstract

This paper presents a new approach for precisely estimating the renal vascular dominant region using a Voronoi diagram. To provide computer-assisted diagnostics for the pre-surgical simulation of partial nephrectomy surgery, we must obtain information on the renal arteries and the renal vascular dominant regions. We propose a fully automatic segmentation method that combines a neural network and tensor-based graph-cut methods to precisely extract the kidney and renal arteries. First, we use a convolutional neural network to localize the kidney regions and extract tiny renal arteries with a tensor-based graph-cut method. Then we generate a Voronoi diagram to estimate the renal vascular dominant regions based on the segmented kidney and renal arteries. The accuracy of kidney segmentation in 27 cases with 8-fold cross validation reached a Dice score of 95%. The accuracy of renal artery segmentation in 8 cases obtained a centerline overlap ratio of 80%. Each partition region corresponds to a renal vascular dominant region. The final dominant-region estimation accuracy achieved a Dice coefficient of 80%. A clinical application showed the potential of our proposed estimation approach in a real clinical surgical environment. Further validation using large-scale database is our future work.

Authors

  • Chenglong Wang
    Plastic Surgery Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, China.
  • Holger R Roth
  • Takayuki Kitasaka
    Graduate School of Information Science, Aichi Institute of Technology, 1247 Yachigusa, Yagusa-cho, Toyota, Aichi, Japan.
  • Masahiro Oda
    Graduate School of Informatics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
  • Yuichiro Hayashi
    Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan.
  • Yasushi Yoshino
    Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Tokunori Yamamoto
    Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Naoto Sassa
    Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Momokazu Goto
    Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Kensaku Mori
    Graduate School of Informatics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.