AIMC Topic: Kidney
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Urinary Complement proteome strongly linked to diabetic kidney disease progression.
Nature communications
Aug 7, 2025
Diabetic kidney disease (DKD) progression is not well understood. Using high-throughput proteomics, biostatistical, pathway and machine learning tools, we examine the urinary Complement proteome in two prospective cohorts with type 1 or 2 diabetes an...
Development and evaluation of deep neural networks for the classification of subtypes of renal cell carcinoma from kidney histopathology images.
Scientific reports
Aug 5, 2025
Kidney cancer is a leading cause of cancer-related mortality, with renal cell carcinoma (RCC) being the most prevalent form, accounting for 80-85% of all renal tumors. Traditional diagnosis of kidney cancer requires manual examination and analysis of...
Natural language processing for kidney ultrasound analysis: correlating imaging reports with chronic kidney disease diagnosis.
Renal failure
Aug 4, 2025
INTRODUCTION: Natural language processing (NLP) has been used to analyze unstructured imaging report data, yet its application in identifying chronic kidney disease (CKD) features from kidney ultrasound reports remains unexplored.
Detection of Unlabeled Polystyrene Micro- and Nanoplastics in Mammalian Tissue by Optical Photothermal Infrared Spectroscopy.
Analytical chemistry
Aug 1, 2025
In this study, we investigate the efficacy of optical photothermal infrared (O-PTIR) spectroscopy, also known as mid-infrared photothermal (MIP) microscopy, for label-free and nondestructive detection of micro- and nanoplastics (MNPs) down to diamete...
Machine learning for the prediction of augmented renal clearance (ARC) in patients with sepsis in critical care units.
Scientific reports
Jul 18, 2025
This study aims to establish and validate prediction models based on novel machine learning (ML) algorithms for augmented renal clearance (ARC) in critically ill patients with sepsis. Patients with sepsis were extracted from the Medical Information M...
Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol.
BMJ open
Jul 17, 2025
INTRODUCTION: Predictive scoring systems support clinicians in decision-making by estimating the prognosis of patients in intensive care units (ICUs). However, there is limited evidence on the accuracy of these systems in predicting mortality and org...
Multimodal deep learning improving the accuracy of pathological diagnoses for membranous nephropathy.
Renal failure
Jul 14, 2025
OBJECTIVES: Renal biopsy is the gold standard for the diagnosis of glomerular diseases including membranous nephropathy (MN), however, it faces challenges in accuracy, objectivity, and reproducibility of tissue evaluation. This study aims to develop ...
Picoeukaryote-based biohybrid microrobots for active delivery in the kidney.
Science advances
Jul 11, 2025
Confined spaces in the human body pose substantial challenges for biomedical procedures. Navigating these ultrasmall environments is essential for precise drug delivery, improving treatment outcomes and reducing adverse effects. Microrobots offer a p...
Cellular senescence in renal ischemia-reperfusion injury.
Chinese medical journal
Jul 7, 2025
Acute kidney injury (AKI) affects more than 20% of hospitalized patients and is a significant contributor to morbidity and mortality, primarily due to ischemia-reperfusion injury (IRI), which is one of the leading causes of AKI. IRI not only exacerba...
Uncovering key markers and therapeutic targets for renal fibrosis in diabetic kidney disease through bulk and single-cell RNA sequencing.
Journal of translational medicine
Jul 4, 2025
BACKGROUND: Diabetic kidney disease (DKD) is the major cause of chronic kidney failure, with tubulointerstitial fibrosis playing a crucial role in disease development. Identifying fibrosis-related genes is crucial for improving diagnosis and developi...
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