A case of fatal multidrug intoxication involving flualprazolam: distribution in body fluids and solid tissues.

Journal: Forensic toxicology
PMID: 36454486

Abstract

PURPOSE: Designer benzodiazepines (DBZDs) increasingly emerged on the novel psychoactive substance (NPS) market in the last few years. They are usually sold as readily available alternatives to prescription benzodiazepines (BZDs) or added to counterfeit medicines. BZDs are generally considered relatively safe drugs due to the low risk of serious acute adverse effects in mono-intoxication, though e.g., alprazolam seems to display an elevated risk of respiratory depression. Here we report on a fatal intoxication involving the novel DBZD flualprazolam.

Authors

  • Arianna Giorgetti
    DIMEC, Department of Medical and Surgical Sciences, University of Bologna, 40126, Bologna, Italy.
  • Michaela J Sommer
    Institute of Forensic Medicine, Medical Center-University of Freiburg, 79104, Freiburg, Germany.
  • Maurice Wilde
    Institute of Forensic Medicine, Medical Center-University of Freiburg, 79104, Freiburg, Germany.
  • Markus Große Perdekamp
    Institute of Forensic Medicine, Medical Center-University of Freiburg, 79104, Freiburg, Germany.
  • Volker Auwärter
    Institute of Forensic Medicine, Medical Center-University of Freiburg, 79104, Freiburg, Germany. volker.auwaerter@uniklinik-freiburg.de.

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