TS-GOEA: a web tool for tissue-specific gene set enrichment analysis based on gene ontology.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: The Gene Ontology (GO) knowledgebase is the world's largest source of information on the functions of genes. Since the beginning of GO project, various tools have been developed to perform GO enrichment analysis experiments. GO enrichment analysis has become a commonly used method of gene function analysis. Existing GO enrichment analysis tools do not consider tissue-specific information, although this information is very important to current research.

Authors

  • Jiajie Peng
    School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China. jiajiepeng@hit.edu.cn.
  • Guilin Lu
    School of Computer Science, Northwestern Polytechnical University, Xi'an, 710129, China.
  • Hansheng Xue
    School of Computer Science, Northwestern Polytechnical University, Xi'an, China.
  • Tao Wang
    Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Xuequn Shang