A practical model for the identification of congenital cataracts using machine learning.

Journal: EBioMedicine
PMID:

Abstract

BACKGROUND: Approximately 1 in 33 newborns is affected by congenital anomalies worldwide. We aimed to develop a practical model for identifying infants with a high risk of congenital cataracts (CCs), which is the leading cause of avoidable childhood blindness.

Authors

  • Duoru Lin
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
  • Jingjing Chen
    Department of Cardiovascular Medicine, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
  • Zhuoling Lin
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Xian Lie South Road 54#, Guangzhou, 510060, China.
  • Xiaoyan Li
    Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, China.
  • Kai Zhang
    Anhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
  • Xiaohang Wu
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Xian Lie South Road 54#, Guangzhou, 510060, China.
  • Zhenzhen Liu
    Department of Functional Science, School of Medicine, Yangtze University, No.1 Nanhuan Road, Jingzhou City 434100, China.
  • Jialing Huang
    School of Public Health, Sun Yat-sen University, Guangzhou, China.
  • Jing Li
    Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Yi Zhu
    2State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong China.
  • Chuan Chen
    Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing 100876, China.
  • Lanqin Zhao
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, China.
  • Yifan Xiang
    2State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong China.
  • Chong Guo
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
  • Liming Wang
    School of Information and Communication Engineering, North University of China, Taiyuan 030051, China. wlm@nuc.edu.cn.
  • Yizhi Liu
    School of Computer Science and Engineering, Hunan University of Science and Technology, Xiangtan, China.
  • Weirong Chen
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
  • Haotian Lin
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou.