Machine learning prediction of oncology drug targets based on protein and network properties.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: The selection and prioritization of drug targets is a central problem in drug discovery. Computational approaches can leverage the growing number of large-scale human genomics and proteomics data to make in-silico target identification, reducing the cost and the time needed.

Authors

  • Zoltán Dezső
    Computational Biology-Genomic Research Center, ABBVIE, Redwood City, CA, USA. zoltan.dezso@abbvie.com.
  • Michele Ceccarelli
    Computational Biology-Genomic Research Center, ABBVIE, Redwood City, CA, USA. michele.ceccarelli@unina.it.