Neural memory plasticity for medical anomaly detection.

Journal: Neural networks : the official journal of the International Neural Network Society
Published Date:

Abstract

In the domain of machine learning, Neural Memory Networks (NMNs) have recently achieved impressive results in a variety of application areas including visual question answering, trajectory prediction, object tracking, and language modelling. However, we observe that the attention based knowledge retrieval mechanisms used in current NMNs restrict them from achieving their full potential as the attention process retrieves information based on a set of static connection weights. This is suboptimal in a setting where there are vast differences among samples in the data domain; such as anomaly detection where there is no consistent criteria for what constitutes an anomaly. In this paper, we propose a plastic neural memory access mechanism which exploits both static and dynamic connection weights in the memory read, write and output generation procedures. We demonstrate the effectiveness and flexibility of the proposed memory model in three challenging anomaly detection tasks in the medical domain: abnormal EEG identification, MRI tumour type classification and schizophrenia risk detection in children. In all settings, the proposed approach outperforms the current state-of-the-art. Furthermore, we perform an in-depth analysis demonstrating the utility of neural plasticity for the knowledge retrieval process and provide evidence on how the proposed memory model generates sparse yet informative memory outputs.

Authors

  • Tharindu Fernando
    The Speech, Audio, Image and Video Technologies (SAIVT) research group, School of Electrical Engineering & Computer Science, Queensland University of Technology, Australia.
  • Simon Denman
    The Speech, Audio, Image and Video Technologies (SAIVT) research group, School of Electrical Engineering & Computer Science, Queensland University of Technology, Australia.
  • David Ahmedt-Aristizabal
    The Speech, Audio, Image and Video Technologies (SAIVT) research group, School of Electrical Engineering & Computer Science, Queensland University of Technology, Australia. Electronic address: david.aristizabal@hdr.qut.edu.au.
  • Sridha Sridharan
    The Speech, Audio, Image and Video Technologies (SAIVT) research group, School of Electrical Engineering & Computer Science, Queensland University of Technology, Australia.
  • Kristin R Laurens
    School of Psychology and Counselling and the Institute of Health Biomedical Innovation (IHBI), Queensland University of Technology, Australia. Electronic address: kristin.laurens@qut.edu.au.
  • Patrick Johnston
    School of Psychology and Counselling and the Institute of Health Biomedical Innovation (IHBI), Queensland University of Technology, Australia. Electronic address: patrick.johnston@qut.edu.au.
  • Clinton Fookes
    The Speech, Audio, Image and Video Technologies (SAIVT) research group, School of Electrical Engineering & Computer Science, Queensland University of Technology, Australia.