[A fusion network model based on limited training samples for the automatic segmentation of pelvic endangered organs].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Published Date:

Abstract

When applying deep learning to the automatic segmentation of organs at risk in medical images, we combine two network models of Dense Net and V-Net to develop a Dense V-network for automatic segmentation of three-dimensional computed tomography (CT) images, in order to solve the problems of degradation and gradient disappearance of three-dimensional convolutional neural networks optimization as training samples are insufficient. This algorithm is applied to the delineation of pelvic endangered organs and we take three representative evaluation parameters to quantitatively evaluate the segmentation effect. The clinical result showed that the Dice similarity coefficient values of the bladder, small intestine, rectum, femoral head and spinal cord were all above 0.87 (average was 0.9); Jaccard distance of these were within 2.3 (average was 0.18). Except for the small intestine, the Hausdorff distance of other organs were less than 0.9 cm (average was 0.62 cm). The Dense V-Network has been proven to achieve the accurate segmentation of pelvic endangered organs.

Authors

  • Qingnan Wu
    Department of Radiation Oncology, Peking University International Hospital, Beijing 102206, P.R.China;School of Physics Science and Technology, Wuhan University, Wuhan 430072, P.R.China.
  • Yunlai Wang
    Department of Radiation Oncology, People's Liberation Army General Hospital, Beijing 100853, P.R.China.
  • Hong Quan
    School of Physics Science and Technology, Wuhan University, Wuhan 430072, P.R.China.
  • Junjie Wang
    School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
  • Shanshan Gu
    Department of Radiation Oncology, People's Liberation Army General Hospital, Beijing 100853, P.R.China.
  • Wei Yang
    Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, PR China. Electronic address: 421063202@qq.com.
  • Ruigang Ge
    Department of Radiation Oncology, People's Liberation Army General Hospital, Beijing 100853, P.R.China.
  • Jie Liu
    School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, China.
  • Zhongjian Ju
    Department of Radiation Oncology, People's Liberation Army General Hospital, Beijing 100853, P.R.China.