Gait variability as digital biomarker of disease severity in Huntington's disease.

Journal: Journal of neurology
Published Date: Feb 11, 2020

Abstract

BACKGROUND: Impaired gait plays an important role for quality of life in patients with Huntington's disease (HD). Measuring objective gait parameters in HD might provide an unbiased assessment of motor deficits in order to determine potential beneficial effects of future treatments.

Authors

  • Heiko Gaßner
    Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
  • Dennis Jensen
    Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
  • F Marxreiter
    Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
  • Anja Kletsch
    George-Huntington Institute (GHI) GmbH, Münster, Germany.
  • Stefan Bohlen
    George-Huntington Institute (GHI) GmbH, Münster, Germany.
  • Robin Schubert
    George-Huntington Institute (GHI) GmbH, Münster, Germany.
  • Lisa M Muratori
    George-Huntington Institute (GHI) GmbH, Münster, Germany.
  • Bjoern Eskofier
  • Jochen Klucken
  • Jürgen Winkler
    Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.
  • Ralf Reilmann
    George Huntington Institute and Department of Radiology University of Münster, Münster, Germany.
  • Zacharias Kohl
    Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany. Zacharias.Kohl@klinik.uni-regensburg.de.

Keywords

External Resources

Popular Topics
Recent Journals