Evaluation of the pharmacokinetic drug-drug interaction between the antiretroviral agents fostemsavir and maraviroc: a single-sequence crossover study in healthy participants.

Journal: HIV research & clinical practice
PMID:

Abstract

BACKGROUND: Fostemsavir is an oral prodrug of temsavir, a first-in-class attachment inhibitor that binds HIV-1 gp120, preventing initial HIV attachment and entry into host immune cells.

Authors

  • Mary Beth Wire
    ViiV Healthcare, Research Triangle Park, NC, USA.
  • Mindy Magee
    GlaxoSmithKline, Upper Providence, PA, USA.
  • Peter Ackerman
    ViiV Healthcare, Branford, CT, USA.
  • Cyril Llamoso
    ViiV Healthcare, Branford, CT, USA.
  • Katy Moore
    ViiV Healthcare, Research Triangle Park, NC, USA.