AIMC Topic: Cross-Over Studies
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Trauma-predictive brain network connectivity adaptively responds to mild acute stress.
Proceedings of the National Academy of Sciences of the United States of America
Jul 30, 2025
Past traumatic experiences shape neural responses to future stress, but the mechanisms underlying this dynamic interaction remain unclear. Here, we assessed how trauma-related brain networks respond to current acute stress in real time. Using a machi...
Machine Learning-Based Cognitive Assessment With The Autonomous Cognitive Examination: Randomized Controlled Trial.
Journal of medical Internet research
Jul 30, 2025
BACKGROUND: The rising prevalence of dementia necessitates a scalable solution to cognitive assessments. The Autonomous Cognitive Examination (ACoE) is a foundational cognitive test for the phenotyping of cognitive symptoms across the primary cogniti...
Enhancing theory of mind in autism through humanoid robot interaction in a randomized controlled trial.
Scientific reports
Jul 29, 2025
Autism Spectrum Disorder presents significant challenges in social cognition, particularly in understanding others' thoughts, emotions, and intentions. Traditional interventions often rely on role-playing games with human therapists or inanimate obje...
Artificial Intelligence to Improve Clinical Coding Practice in Scandinavia: Crossover Randomized Controlled Trial.
Journal of medical Internet research
Jul 3, 2025
BACKGROUND: Clinical coding is critical for hospital reimbursement, quality assessment, and health care planning. In Scandinavia, however, coding is often done by junior doctors or medical secretaries, leading to high rates of coding errors. Artifici...
Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.
Clinical nutrition (Edinburgh, Scotland)
Jun 25, 2025
BACKGROUND & AIMS: Studies in-vitro and in animals propose that vitamins and minerals can alter the human gut microbiome. Human trials replicating these findings are scarce or used micronutrient supplementation in supraphysiological doses. We explore...
Physiological comparison of noninvasive ventilation and high-flow nasal oxygen on inspiratory efforts and tidal volumes after extubation: a randomized crossover trial.
Critical care (London, England)
May 8, 2025
BACKGROUND: Extubation failure leading to reintubation is associated with high mortality. In patients at high-risk of extubation failure, clinical practice guidelines recommend prophylactic non-invasive ventilation (NIV) over high-flow nasal oxygen (...
Deep learning-assisted detection of meniscus and anterior cruciate ligament combined tears in adult knee magnetic resonance imaging: a crossover study with arthroscopy correlation.
International orthopaedics
Apr 28, 2025
AIM: We aimed to compare the diagnostic performance of physicians in the detection of arthroscopically confirmed meniscus and anterior cruciate ligament (ACL) tears on knee magnetic resonance imaging (MRI), with and without assistance from a deep lea...
Effect of Uncertainty-Aware AI Models on Pharmacists' Reaction Time and Decision-Making in a Web-Based Mock Medication Verification Task: Randomized Controlled Trial.
JMIR medical informatics
Apr 18, 2025
BACKGROUND: Artificial intelligence (AI)-based clinical decision support systems are increasingly used in health care. Uncertainty-aware AI presents the model's confidence in its decision alongside its prediction, whereas black-box AI only provides a...
Robotic beds for the treatment of positional obstructive sleep apnea - A randomized cross-over pilot trial.
Sleep medicine
Feb 20, 2025
BACKGROUND: Interventions leading to avoidance of supine position and thus reducing the likelihood of upper airway collapse during sleep are a treatment approach for positional obstructive sleep apnea (POSA). The aim of this randomized cross-over tri...
Network Analysis and Machine Learning for Signal Detection and Prioritization Using Electronic Healthcare Records and Administrative Databases: A Proof of Concept in Drug-Induced Acute Myocardial Infarction.
Drug safety
Feb 7, 2025
BACKGROUND: Safety signals for potential drug-induced adverse events (AEs) typically emerge from multiple data sources, primarily spontaneous reporting systems, despite known limitations. Increasingly, real-world data from sources such as electronic ...
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