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Evaluation of the pharmacokinetic drug-drug interaction between the antiretroviral agents fostemsavir and maraviroc: a single-sequence crossover study in healthy participants.

HIV research & clinical practice 35285786
BACKGROUND: Fostemsavir is an oral prodrug of temsavir, a first-in-class attachment inhibitor that binds HIV-1 gp120, preventing initial HIV attachment and entry into host immune cells.
Adult Anti-HIV Agents Anti-Retroviral Agents Cross-Over Studies Drug Interactions Healthy Volunteers Humans Maraviroc Organophosphates Piperazines
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