Robotic compounding versus manual compounding of chemotherapy: Comparing dosing accuracy and precision.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published Date:

Abstract

BACKGROUND: Cytostatic drugs are increasingly being prepared with a cytostatic robot, though it is not known whether the dose of the final product is more accurate after automated or manual preparation. This study is the first to compare accuracy and precision of automated preparations with manual preparations by measuring volumes and drug concentrations.

Authors

  • T H Geersing
    OLVG, Department of Clinical Pharmacy, Amsterdam, the Netherlands.
  • M G Klous
    OLVG, Department of Clinical Pharmacy, Amsterdam, the Netherlands.
  • E J F Franssen
    OLVG, Department of Clinical Pharmacy, Amsterdam, the Netherlands.
  • J J G van den Heuvel
    OLVG, Department of Clinical Pharmacy, Amsterdam, the Netherlands.
  • M Crul
    Amsterdam University Medical Center, Department of Clinical Pharmacology and Pharmacy, Amsterdam, the Netherlands. Electronic address: m.crul@vumc.nl.