Review of Artificial Intelligence Applications and Algorithms for Brain Organoid Research.

Journal: Interdisciplinary sciences, computational life sciences
Published Date: Aug 24, 2020

Abstract

The human brain organoid is a miniature three-dimensional tissue culture that can simulate the structure and function of the brain in an in vitro culture environment. Although we consider that human brain organoids could be used to understand brain development and diseases, experimental models of human brain organoids are so highly variable that we apply artificial intelligence (AI) techniques to investigate the development mechanism of the human brain. Therefore, this study briefly reviewed commonly used AI applications for human brain organoid-magnetic resonance imaging, electroencephalography, and gene editing techniques, as well as related AI algorithms. Finally, we discussed the limitations, challenges, and future study direction of AI-based technology for human brain organoids.

Authors

  • Jiayidaer Badai
    College of Computer Science, Sichuan University, Chengdu, 610065, China.
  • Qian Bu
    Department of Food Engineering, College of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China.
  • Le Zhang
    State Key Laboratory of Multiphase Complex Systems, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; College of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, China; Key Laboratory of Science and Technology on Particle Materials, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 361021, China.

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