Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet.

Journal: Expert review of clinical pharmacology
Published Date:

Abstract

INTRODUCTION: Technical and logical breakthroughs have provided new opportunities in medicine to use knowledge bases and large-scale clinical data (real-world) at point-of-care as part of a learning healthcare system to diminish the knowledge-practice gap.

Authors

  • Mikael Hoffmann
    The NEPI Foundation - Swedish Network for Pharmacoepidemiology, Linköping University , Linköping, Sweden.
  • Robert Vander Stichele
    Clinical Pharmacology Research Unit, Heymans Institute of Pharmacology, Ghent University , Ghent, Belgium.
  • David W Bates
    Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
  • Johanna Björklund
    Department of Computing Science, Umeå University , Umeå, Sweden.
  • Steve Alexander
    School of Life Sciences, University of Nottingham Medical School , Nottingham, UK.
  • Marine L Andersson
    Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden.
  • Ane Auraaen
    Organisation for Economic Cooperation and Development (OECD) , Paris, France.
  • Marion Bennie
    Public Health and Intelligence Strategic Business Unit, NHS National Services Scotland, Edinburgh, UK.
  • Marja-Liisa Dahl
    Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden.
  • Birgit Eiermann
    Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden.
  • Werner Hackl
    Institute of Medical Informatics, UMIT-Private University for Health Sciences, Medical Informatics and Technology , Hall in Tirol, Austria.
  • Tora Hammar
    E-health Institute, Department of Medicine and Optometry, Linnaeus University , Kalmar, Sweden.
  • Paul Hjemdahl
    Clinical Pharmacology Unit, Clinical Epidemiology Division, Department of Medicine, Karolinska Institutet , Stockholm, Sweden.
  • Sabine Koch
    Health Informatics Centre, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet , Stockholm, Sweden.
  • Ilkka Kunnamo
    The Finnish Medical Society Duodecim , Helsinki, Finland.
  • Herve Le Louët
    Council for International Organizations of Medical Sciences (CIOMS) , Geneva, Switzerland.
  • Papapetrou Panagiotis
    Department of Computer and Systems Science, Stockholm University , Stockholm, Sweden.
  • Lembit Rägo
    Council for International Organizations of Medical Sciences (CIOMS) , Geneva, Switzerland.
  • Michael Spedding
    International Union of Basic and Clinical Pharmacology (IUPHAR) , Paris, France.
  • Hanna M Seidling
    Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg University , Heidelberg, Germany.
  • Dina Demner-Fushman
    Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, MD.
  • Lars L Gustafsson
    Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden.