Hybrid Assistive Limb® for sporadic inclusion body myositis: A case series.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
PMID:

Abstract

We evaluated the efficacy of rehabilitation therapy with Hybrid Assistive Limb® (HAL; hereafter HAL therapy) in three patients diagnosed with sporadic inclusion body myositis (sIBM) who were hospitalized to undergo HAL therapy. Among them, one patient participated in eight courses and the other two in two courses of HAL therapy between 2017 and 2020. We determined the mean rate of improvement in two-minute walking distance and 6 m walking speed at the time of hospital discharge. After HAL therapy, we confirmed the patients' desire to continue the use of HAL. In one patient, we observed improvements of 146.0% and 120.0% in two-minute walk and 6 m walking speed, respectively, after the first course of HAL therapy; these values are 133.7% and 130% after the eighth course of HAL therapy. These values exceeded 90% in the other two patients after the second course of HAL therapy. HAL therapy maintained both quantity and quality of ambulation and showed positive psychological effects on patient conditions because it reduces exercise load and facilitates safety. While HAL therapy might be effective in maintaining and improving ambulation in patients with sIBM, we should consider to discontinue HAL therapy as it increased risk of falling.

Authors

  • Naoki Suzuki
    Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima, Hiroshima, Japan.
  • Temma Soga
    Department of Neurology, Shodo-kai Southern Tohoku General Hospital, 1-2-5, Satonomori, Iwanuma, Miyagi, Japan.
  • Rumiko Izumi
    Department of Neurology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Japan.
  • Masaya Toyoshima
    Department of Neurology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Japan.
  • Miwako Shibasaki
    Department of Neurology, Shodo-kai Southern Tohoku General Hospital, 1-2-5, Satonomori, Iwanuma, Miyagi, Japan.
  • Itsumi Sato
    Department of Neurology, Shodo-kai Southern Tohoku General Hospital, 1-2-5, Satonomori, Iwanuma, Miyagi, Japan.
  • Yu Kudo
    Department of Neurology, Shodo-kai Southern Tohoku General Hospital, 1-2-5, Satonomori, Iwanuma, Miyagi, Japan.
  • Masashi Aoki
    Department of Neurology (S.N., T.M., Y.T., K.T., N.Y., H.K., M.A.), Department of Multiple Sclerosis Therapeutics (T.M.), Department of Neurosurgery (R.S., T.T.), and Department of Pathology (M.W.), Tohoku University Graduate School of Medicine, Sendai; Department of Anatomic Pathology (Y.S.-H.), Tokyo Medical University; Department of Virology 1 (K.N., M.S.), Laboratory of Neurovirology, National Institute of Infectious Diseases; Department of Neurology (I.N.), Tohoku Medical and Pharmaceutical University, Sendai; and Department of Multiple Sclerosis Therapeutics (K.F.), Fukushima Medical University School of Medicine and Multiple Sclerosis and Neuromyelitis Optica Center, Southern TOHOKU Research Institute for Neuroscience, Japan.
  • Masaaki Kato
    Department of Neurology, Shodo-kai Southern Tohoku General Hospital, 1-2-5, Satonomori, Iwanuma, Miyagi, Japan; Department of Neurology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Japan. Electronic address: katom@mui.biglobe.ne.jp.