Complete abdomen and pelvis segmentation using U-net variant architecture.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: Organ segmentation of computed tomography (CT) imaging is essential for radiotherapy treatment planning. Treatment planning requires segmentation not only of the affected tissue, but nearby healthy organs-at-risk, which is laborious and time-consuming. We present a fully automated segmentation method based on the three-dimensional (3D) U-Net convolutional neural network (CNN) capable of whole abdomen and pelvis segmentation into 33 unique organ and tissue structures, including tissues that may be overlooked by other automated segmentation approaches such as adipose tissue, skeletal muscle, and connective tissue and vessels. Whole abdomen segmentation is capable of quantifying exposure beyond a handful of organs-at-risk to all tissues within the abdomen.

Authors

  • Alexander D Weston
    Radiology Informatics Laboratory, Department of Radiology, Mayo Clinic, Rochester, Minnesota.
  • Panagiotis Korfiatis
    From the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
  • Kenneth A Philbrick
    1 Department of Radiology, Radiology Informatics Laboratory, Mayo Clinic, 3507 17th Ave NW, Rochester, MN 55901.
  • Gian Marco Conte
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
  • Petro Kostandy
    From the Department of Biomedical Engineering and Physiology (A.D.W.) and Department of Radiology (P.K., T.L.K., K.A.P., P.K., T.S., M.S., N.T., B.J.E.), Mayo Clinic, 200 First St SW, Rochester, MN 55905.
  • Thomas Sakinis
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
  • Atefeh Zeinoddini
    Radiology Informatics Laboratory, Department of Radiology, Mayo Clinic, Rochester, MN, USA.
  • Arunnit Boonrod
    Radiology Informatics Laboratory, Department of Radiology, Mayo Clinic, Rochester, MN, USA.
  • Michael Moynagh
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
  • Naoki Takahashi
    1 Department of Radiology, Radiology Informatics Laboratory, Mayo Clinic, 3507 17th Ave NW, Rochester, MN 55901.
  • Bradley J Erickson
    Department of Radiology, Radiology Informatics Lab, Mayo Clinic, Rochester, MN 55905, United States.