Machine learning models predict coagulopathy in spontaneous intracerebral hemorrhage patients in ER.

Journal: CNS neuroscience & therapeutics
PMID: 33249760

Abstract

AIMS: Coagulation abnormality is one of the primary concerns for patients with spontaneous intracerebral hemorrhage admitted to ER. Conventional laboratory indicators require hours for coagulopathy diagnosis, which brings difficulties for appropriate intervention within the optimal window. This study evaluates the possibility of building efficient coagulopathy prediction models using data mining and machine learning algorithms.

Authors

  • Fengping Zhu
    Department of Neurosurgery, Huahsan Hospital, Fudan University, Shanghai, China.
  • Zhiguang Pan
    Department of Neurosurgery, Huahsan Hospital, Fudan University, Shanghai, China.
  • Ying Tang
    Department of Ultrasound, Tianjin First Central Hospital, NanKai University, Tianjin, 300192, China. drtang2002@aliyun.com.
  • Pengfei Fu
    Department of Neurosurgery, Huahsan Hospital, Fudan University, Shanghai, China.
  • Sijie Cheng
    Information Center, Huahsan Hospital, Fudan University, Shanghai, China.
  • Wenzhong Hou
    Information Center, Huahsan Hospital, Fudan University, Shanghai, China.
  • Qi Zhang
    Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
  • Hong Huang
    Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland, Department of Microbiology and Immunology and Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore MD, USA, SIB Swiss Institute of Bioinformatics, 1 Rue Michel Servet, 1211 Geneva, Switzerland, Department of Medicine and Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore MD, USA, Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94158, USA, School of Information, University of South Florida, Tampa, FL, 33647, USA, Genomics Division, Lawrence Berkeley National Lab, 1 Cyclotron Rd., Berkeley, 94720 CA USA, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK, Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, Geneva, Switzerland, ETH Zurich, Department of Computer Science, Universitätstr. 19, 8092 Zürich, Switzerland, SIB Swiss Institute of Bioinformatics, Universitätstr. 6, 8092 Zürich, Switzerland and University College London, Gower St, London WC1E 6BT, UK.
  • Yirui Sun
    Department of Neurosurgery, Huahsan Hospital, Fudan University, Shanghai, China.

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