BACKGROUND: Liver failure often results in significant coagulation dysfunction, which is a major complication. Artificial liver support systems (ALSS) have been used to ameliorate coagulation parameters, but the dynamic nature of these improvements a...
BACKGROUND: Early intervention in patients with major traumatic injuries is critical. Decision support can improve clinicians' ability to identify high-risk patients. The aim of this study was to compare the performance of a machine-learning (ML) dec...
Despite advancements in trauma care, uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) remain the leading causes of preventable deaths after trauma. Understanding the genetic underpinnings and molecular mechanisms of TIC is crucial for de...
BACKGROUND: Sepsis-induced coagulopathy (SIC) is a complex condition characterized by systemic inflammation and coagulopathy. This study aimed to develop and validate a machine learning (ML) model to predict SIC risk in patients with sepsis.
BACKGROUND: Recent research has revealed the potential value of machine learning (ML) models in improving prognostic prediction for patients with trauma. ML can enhance predictions and identify which factors contribute the most to posttraumatic morta...
The journal of trauma and acute care surgery
Sep 27, 2024
BACKGROUND: Acute traumatic coagulopathy (ATC) is a well-described phenomenon known to begin shortly after injury. This has profound implications for resuscitation from hemorrhagic shock, as ATC is associated with increased risk for massive transfusi...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 12, 2023
BACKGROUND AND PURPOSE: MRI-only planning relies on dosimetrically accurate synthetic-CT (sCT) generation to allow dose calculation. Here we validated the dosimetric accuracy of sCTs generated using a deep learning algorithm for pelvic, brain and hea...
Burns : journal of the International Society for Burn Injuries
Dec 15, 2020
BACKGROUND: Patients with severe burns often show systemic coagulation changes in the early stage and even develop extensive coagulopathy. Previous studies have confirmed that soluble TREM-like transcript-1 (sTLT-1) mediates a novel mechanism of haem...
AIMS: Coagulation abnormality is one of the primary concerns for patients with spontaneous intracerebral hemorrhage admitted to ER. Conventional laboratory indicators require hours for coagulopathy diagnosis, which brings difficulties for appropriate...
OBJECTIVE: Mortality following surgical resection of spinal tumors is a devastating outcome. Naïve Bayes machine learning algorithms may be leveraged in surgical planning to predict mortality. In this investigation, we use a Naïve Bayes classificatio...
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