Machine learning in cardiovascular radiology: ESCR position statement on design requirements, quality assessment, current applications, opportunities, and challenges.

Journal: European radiology
Published Date:

Abstract

Machine learning offers great opportunities to streamline and improve clinical care from the perspective of cardiac imagers, patients, and the industry and is a very active scientific research field. In light of these advances, the European Society of Cardiovascular Radiology (ESCR), a non-profit medical society dedicated to advancing cardiovascular radiology, has assembled a position statement regarding the use of machine learning (ML) in cardiovascular imaging. The purpose of this statement is to provide guidance on requirements for successful development and implementation of ML applications in cardiovascular imaging. In particular, recommendations on how to adequately design ML studies and how to report and interpret their results are provided. Finally, we identify opportunities and challenges ahead. While the focus of this position statement is ML development in cardiovascular imaging, most considerations are relevant to ML in radiology in general. KEY POINTS: • Development and clinical implementation of machine learning in cardiovascular imaging is a multidisciplinary pursuit. • Based on existing study quality standard frameworks such as SPIRIT and STARD, we propose a list of quality criteria for ML studies in radiology. • The cardiovascular imaging research community should strive for the compilation of multicenter datasets for the development, evaluation, and benchmarking of ML algorithms.

Authors

  • Thomas Weikert
    From the Department of Radiology, University Hospital Basel, Basel, Switzerland.
  • Marco Francone
    Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Policlinico Umberto I, V.le Regina Elena 324, 00161, Rome, Italy.
  • Suhny Abbara
    Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9316, USA.
  • Bettina Baeßler
    Department of Radiology, University Hospital of Cologne, Cologne, Germany.
  • Byoung Wook Choi
  • Matthias Gutberlet
    Department of Diagnostic and Interventional Radiology, Heart Center Leipzig - University Leipzig, Strümpellstrasse 39, 04289, Leipzig, Germany.
  • Elizabeth M Hecht
    Department of Radiology, Weill Cornell Medicine, 520 East 70th Street, New York, NY, 10021, USA.
  • Christian Loewe
    Division of Cardiovascular and Interventional Radiology, Department of Bioimaging and Image-Guided Therapy, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
  • Elie Mousseaux
    Department of Radiology, Hôpital Européen Georges Pompidou, APHP, University of Paris & INSERM, U970 29 rue Leblanc, 75015, Paris, France.
  • Luigi Natale
    Radiological and Haematological Sciences Department, Fondazione Policlinico Universitario A. Gemelli- IRCCS, Università Cattolica S. Cuore, Largo Agostino Gemelli 8, 00168, Rome, Italy.
  • Konstantin Nikolaou
    Department of Diagnostic and Interventional Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str.3, 72076 Tübingen, Germany.
  • Karen G Ordovas
    Department of Radiology and Biomedical Imaging, University of California San Francisco.
  • Charles Peebles
    Department of Radiology, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.
  • Claudia Prieto
    School of Biomedical Engineering & Imaging Sciences, King's College, London, UK.
  • Rodrigo Salgado
    Department of Radiology, Antwerp University Hospital & Holy Heart Hospital Lier, Wilrijkstraat 10, 2650, Edegem, Belgium.
  • Birgitta Velthuis
    Department of Radiology, Utrecht University Medical Center, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
  • Rozemarijn Vliegenthart
    University of Groningen, University Medical Center Groningen, Department of Radiology, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Jens Bremerich
    University Hospital Basel, Clinic of Radiology & Nuclear Medicine, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.
  • Tim Leiner
    Departments of Radiology and Nuclear Medicine (C.P.S.B., A.J.N., P.v.O., R.N.P.) and Cardiology (S.M.B.), Amsterdam University Medical Centers, Location Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands (J.J.M.W.); Department of Research and Development, Pie Medical Imaging BV, Maastricht, the Netherlands (J.P.A.); and Departments of Cardiology (G.P.B., S.A.J.C.) and Radiology (T.L.), University Medical Center Utrecht, Utrecht, the Netherlands.