Machine Learning Algorithm Validation: From Essentials to Advanced Applications and Implications for Regulatory Certification and Deployment.

Journal: Neuroimaging clinics of North America
Published Date:

Abstract

The deployment of machine learning (ML) models in the health care domain can increase the speed and accuracy of diagnosis and improve treatment planning and patient care. Translating academic research to applications that are deployable in clinical settings requires the ability to generalize and high reproducibility, which are contingent on a rigorous and sound methodology for the development and evaluation of ML models. This article describes the fundamental concepts and processes for ML model evaluation and highlights common workflows. It concludes with a discussion of the requirements for the deployment of ML models in clinical settings.

Authors

  • Farhad Maleki
    Augmented Intelligence & Precision Health Laboratory (AIPHL), Department of Radiology and Research Institute of the McGill University Health Centre, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada.
  • Nikesh Muthukrishnan
    Augmented Intelligence & Precision Health Laboratory (AIPHL), Department of Radiology & Research Institute of the McGill University Health Centre, 5252 Boulevard de Maisonneuve Ouest, Montreal, Quebec H4A 3S5, Canada.
  • Katie Ovens
    Augmented Intelligence & Precision Health Laboratory (AIPHL), Department of Radiology & Research Institute of the McGill University Health Centre, 5252 Boulevard de Maisonneuve Ouest, Montreal, Quebec H4A 3S5, Canada; University of Saskatchewan, 116 - 110 Science Place, Saskatoon, SK S7N 5C9, Canada.
  • Caroline Reinhold
    Department of Radiology, McGill University Health Center, Montréal, Québec, Canada.
  • Reza Forghani
    Department of Radiology, McGill University Health Centre, 1001 Decarie Blvd, Room C02.5821, Montreal, QC, Canada H4A 3J1; Augmented Intelligence & Precision Health Laboratory (AIPHL), Research Institute of the McGill University Health Centre, Montreal, Canada; Segal Cancer Centre and Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada; Gerald Bronfman Department of Oncology, McGill University, Montreal, Canada; and Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Canada.