Distinguishing among neuroinflammatory demyelinating diseases of the central nervous system can present a significant diagnostic challenge due to substantial overlap in clinical presentations and imaging features. Collaboration between specialists, n...
BACKGROUND: Alzheimer's disease (AD) is the principal cause of dementia and requires the early diagnosis of people with mild cognitive impairment (MCI) who are at high risk of progressing. Early diagnosis is imperative for optimizing clinical managem...
Alzheimer's disease (AD) presents a pressing global health challenge, demanding improved strategies for early detection and understanding its progression. In this study, we address this need by employing survival analysis techniques to predict transi...
Machine learning (ML) has significantly transformed biomedical research, leading to a growing interest in model development to advance classification accuracy in various clinical applications. However, this progress raises essential questions regardi...
Early diagnosis of Alzheimer's disease (AD) and its precursor, mild cognitive impairment (MCI), is critical for effective prevention and treatment. Computer-aided diagnosis using magnetic resonance imaging (MRI) provides a cost-effective and objectiv...
Journal of neuroengineering and rehabilitation
Jul 5, 2025
BACKGROUND: Hand dysfunction significantly affects independence after stroke, with outcomes varying across individuals. Exploring biomarkers associated with the paretic hand can improve the prognosis and guide personalized rehabilitation. However, wh...
Correlation matrices serve as fundamental representations of functional brain networks in neuroimaging. Conventional analyses often treat pairwise interactions independently within Euclidean space, neglecting the underlying geometry of correlation st...
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that significantly impacts cognitive function, posing a major global health challenge. Despite its rising prevalence, particularly in low and middle-income countries, early diagnosi...
BMC medical informatics and decision making
Jul 1, 2025
Alzheimer's Disease (AD) poses a significant global health challenge, necessitating early and accurate diagnosis to enable timely interventions. AD is a progressive neurodegenerative disorder that affects millions worldwide and is one of the leading ...
Clinical two-dimensional (2D) MRI data has seen limited application in the early diagnosis of Parkinson's disease (PD) and multiple system atrophy (MSA) due to quality limitations, yet its diagnostic and therapeutic potential remains underexplored. T...
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