The machine learning algorithm for the diagnosis of schizophrenia on the basis of gene expression in peripheral blood.

Journal: Neuroscience letters
PMID:

Abstract

BACKGROUND: Schizophrenia (SCZ) is a highly heritable mental disorder with a substantial disease burden. Machine learning (ML) method can be used to identify individuals with SCZ on the basis of blood gene expression data with high accuracy.

Authors

  • Lulu Zhu
    School of Public Health of Guangxi Medical University, Nanning, Guangxi, China.
  • Xulong Wu
    School of Public Health of Guangxi Medical University, Nanning, Guangxi, China.
  • Bingyi Xu
    School of Public Health of Guangxi Medical University, Nanning, Guangxi, China.
  • Zhi Zhao
    Department of Orthopedics, Laboratory of Tissue and Transplant in Anhui Province, the First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui, 233003, P.R.China.
  • Jialei Yang
    School of Public Health of Guangxi Medical University, Nanning, Guangxi, China.
  • Jianxiong Long
    School of Public Health of Guangxi Medical University, Nanning, Guangxi, China. Electronic address: longjx12345@163.com.
  • Li Su
    China-UK Centre for Cognition and Ageing Research, Faculty of Psychology, Southwest University, Chongqing, China.