Schizophrenia is a complicated mental condition marked by disruptions in thought processes, perceptions, and emotional responses, which can cause severe impairment in everyday functioning. sMRI is a non-invasive neuroimaging technology that visualize...
Clozapine is widely regarded as one of the most effective therapeutics for treatment-resistant schizophrenia. Despite its proven efficacy, the therapeutic use of clozapine is complicated by its narrow therapeutic index, which necessitates rapid and p...
Schizophrenia (SZ) is a complex mental disorder characterized by a profound disruption in cognition and emotion, often resulting in a distorted perception of reality. Magnetic resonance imaging (MRI) is an essential tool for diagnosing SZ which helps...
Schizophrenia is a severe yet treatable mental disorder, and it is diagnosed using a multitude of primary and secondary symptoms. Diagnosis and treatment for each individual depends on the severity of the symptoms. Therefore, there is a need for accu...
BACKGROUND: Early identification of Schizophrenia Spectrum Disorder (SSD) is crucial for effective intervention and prognosis improvement. Previous neuroimaging-based classifications have primarily focused on chronic, medicated SSD cohorts. However, ...
Schizophrenia (SZ) and bipolar disorder (BD) pose diagnostic challenges due to overlapping clinical symptoms and genetic factors, often resulting in misdiagnosis and suboptimal treatment outcomes. This study aimed to identify EEG-based biomarkers tha...
There is a notable need of quantifiable and objective methods for the classification of schizophrenia. Patients with schizophrenia exhibit atypical eye movements compared with healthy individuals. To address this need, we have developed a classificat...
BACKGROUND AND OBJECTIVE: Accurate detection of schizophrenia poses a grand challenge as a complex and heterogeneous mental disorder. Current diagnostic criteria rely primarily on clinical symptoms, which may not fully capture individual differences ...
BACKGROUND: Accurate genetic risk prediction and understanding the mechanisms underlying complex diseases are essential for effective intervention and precision medicine. However, current methods often struggle to capture the intricate and subtle gen...
. Functional network connectivity (FNC) estimated from resting-state functional magnetic resonance imaging showed great information about the neural mechanism in different brain disorders. But previous research has mainly focused on standard statisti...