Investigating Predictors of Preserved Cognitive Function in Older Women Using Machine Learning: Women's Health Initiative Memory Study.

Journal: Journal of Alzheimer's disease : JAD
PMID:

Abstract

BACKGROUND: Identification of factors that may help to preserve cognitive function in late life could elucidate mechanisms and facilitate interventions to improve the lives of millions of people. However, the large number of potential factors associated with cognitive function poses an analytical challenge.

Authors

  • Ramon Casanova
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.
  • Sarah A Gaussoin
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Robert Wallace
    College of Public Health, University of Iowa, Iowa City, IA, USA.
  • Laura D Baker
    Department of Gerontology and Geriatrics, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Jiu-Chiuan Chen
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
  • JoAnn E Manson
    Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Victor W Henderson
    Department of Epidemiology and Population Health and of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
  • Bonnie C Sachs
    Department of Social Sciences & Health Policy, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Jamie N Justice
    Department of Gerontology and Geriatrics, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Eric A Whitsel
    Department of Epidemiology, Gillings School of Global Public Health and Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
  • Kathleen M Hayden
    Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Stephen R Rapp
    Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC, USA.