Automatic Prediction of Recurrence of Major Cardiovascular Events: A Text Mining Study Using Chest X-Ray Reports.

Journal: Journal of healthcare engineering
Published Date:

Abstract

METHODS: We used EHR data of patients included in the Second Manifestations of ARTerial disease (SMART) study. We propose a deep learning-based multimodal architecture for our text mining pipeline that integrates neural text representation with preprocessed clinical predictors for the prediction of recurrence of major cardiovascular events in cardiovascular patients. Text preprocessing, including cleaning and stemming, was first applied to filter out the unwanted texts from X-ray radiology reports. Thereafter, text representation methods were used to numerically represent unstructured radiology reports with vectors. Subsequently, these text representation methods were added to prediction models to assess their clinical relevance. In this step, we applied logistic regression, support vector machine (SVM), multilayer perceptron neural network, convolutional neural network, long short-term memory (LSTM), and bidirectional LSTM deep neural network (BiLSTM).

Authors

  • Ayoub Bagheri
    Department of Methodology and Statistics, Faculty of Social Sciences, Utrecht University, Utrecht, Netherlands.
  • T Katrien J Groenhof
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands.
  • Folkert W Asselbergs
  • Saskia Haitjema
    Central Diagnostic Laboratory, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Michiel L Bots
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands.
  • Wouter B Veldhuis
    Department of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, 3584 CX, the Netherlands.
  • Pim A de Jong
    University Medical Center, Utrecht, The Netherlands.
  • Daniel L Oberski
    Department of Methodology and Statistics, Faculty of Social Sciences, Utrecht University, Utrecht, Netherlands.