ai-corona: Radiologist-assistant deep learning framework for COVID-19 diagnosis in chest CT scans.

Journal: PloS one
PMID:

Abstract

The development of medical assisting tools based on artificial intelligence advances is essential in the global fight against COVID-19 outbreak and the future of medical systems. In this study, we introduce ai-corona, a radiologist-assistant deep learning framework for COVID-19 infection diagnosis using chest CT scans. Our framework incorporates an EfficientNetB3-based feature extractor. We employed three datasets; the CC-CCII set, the MasihDaneshvari Hospital (MDH) cohort, and the MosMedData cohort. Overall, these datasets constitute 7184 scans from 5693 subjects and include the COVID-19, non-COVID abnormal (NCA), common pneumonia (CP), non-pneumonia, and Normal classes. We evaluate ai-corona on test sets from the CC-CCII set, MDH cohort, and the entirety of the MosMedData cohort, for which it gained AUC scores of 0.997, 0.989, and 0.954, respectively. Our results indicates ai-corona outperforms all the alternative models. Lastly, our framework's diagnosis capabilities were evaluated as assistant to several experts. Accordingly, We observed an increase in both speed and accuracy of expert diagnosis when incorporating ai-corona's assistance.

Authors

  • Mehdi Yousefzadeh
    School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
  • Parsa Esfahanian
    School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
  • Seyed Mohammad Sadegh Movahed
    Department of Physics, Shahid Beheshti University, Tehran, Iran.
  • Saeid Gorgin
    School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
  • Dara Rahmati
    School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
  • Atefeh Abedini
    Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Seyed Alireza Nadji
    Virology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
  • Sara Haseli
    Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
  • Mehrdad Bakhshayesh Karam
    Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
  • Arda Kiani
    Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Meisam Hoseinyazdi
    Department of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Jafar Roshandel
    Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
  • Reza Lashgari
    Brain Engineering Research Center, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.