Automatic segmentation of white matter hyperintensities from brain magnetic resonance images in the era of deep learning and big data - A systematic review.

Journal: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Published Date:

Abstract

BACKGROUND: White matter hyperintensities (WMH), of presumed vascular origin, are visible and quantifiable neuroradiological markers of brain parenchymal change. These changes may range from damage secondary to inflammation and other neurological conditions, through to healthy ageing. Fully automatic WMH quantification methods are promising, but still, traditional semi-automatic methods seem to be preferred in clinical research. We systematically reviewed the literature for fully automatic methods developed in the last five years, to assess what are considered state-of-the-art techniques, as well as trends in the analysis of WMH of presumed vascular origin.

Authors

  • Ramya Balakrishnan
    Edinburgh Imaging Academy, University of Edinburgh, Edinburgh, UK; International Institute of Health Sciences, Sri Lanka.
  • Maria Del C Valdés Hernández
    Department of Neuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
  • Andrew J Farrall
    Edinburgh Imaging Academy, University of Edinburgh, Edinburgh, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.