AIMC Topic: White Matter
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Integrative transcriptomic analysis reveals oligodendrocyte lineage switching in multiple sclerosis.
Life science alliance
Aug 4, 2025
Multiple sclerosis (MS) is a chronic disease of the central nervous system. The occurrence of MS is a phased process while its cause is still unclear. Here, by combining white matter single-nucleus transcriptomic datasets from MS and control samples,...
The association between cerebral small vessel disease and unfavorable hematoma morphology in primary intracerebral hemorrhage.
Annals of medicine
Jul 13, 2025
OBJECTIVE: To study the association between cerebral small vessel diseases (CSVD) and unfavorable hematoma morphology in primary intracerebral hemorrhage (ICH).
Enhanced particle swarm optimization for feature selection in SVM-based Alzheimer's disease diagnosis.
Scientific reports
Jul 7, 2025
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder marked by neuronal loss, leading to cognitive and behavioral decline. With the aging global population, AD incidence and its socioeconomic burden are increasing. Developing effectiv...
Disrupted functional topology of the white matter connectome in rhegmatogenous retinal detachment: insights from graph theory and machine learning.
Neuroreport
Jun 24, 2025
BACKGROUND: Rhegmatogenous retinal detachment (RRD) is known to induce functional alterations in the gray matter regions associated with vision. However, the impact of RRD on the white matter (WM) connectome remains largely unexplored.
BrainTract: segmentation of white matter fiber tractography and analysis of structural connectivity using hybrid convolutional neural network.
Neuroscience
Jun 19, 2025
Tractography uses diffusion Magnetic Resonance Imaging (dMRI) to noninvasively reconstruct brain white matter (WM) tracts, with Convolutional Neural Network (CNNs) like U-Net significantly advancing accuracy in medical image segmentation. This work p...
Predicting treatment response in individuals with major depressive disorder using structural MRI-based similarity features.
BMC psychiatry
May 26, 2025
BACKGROUND: Major Depressive Disorder (MDD) is a prevalent mental health condition with significant societal impact. Structural magnetic resonance imaging (sMRI) and machine learning have shown promise in psychiatry, offering insights into brain abno...
The value of radiomics features of white matter hyperintensities in diagnosing cognitive frailty: a study based on T2-FLAIR imaging.
BMC medical imaging
May 22, 2025
BACKGROUND: White matter hyperintensities (WMHs) are closely associated with cognitive frailty (CF). This study aims to explore the potential diagnostic value of WMHs for CF based on radiomics approaches, thereby providing a novel methodology for the...
Relevance of choroid plexus volumes in multiple sclerosis.
Fluids and barriers of the CNS
May 8, 2025
BACKGROUND: The choroid plexus (ChP) plays a pivotal role in inflammatory processes that occur in multiple sclerosis (MS). The enlargement of the ChP in relapsing-remitting multiple sclerosis (RRMS) is considered to be an indication of disease activi...
Automated Quantification of Cerebral Microbleeds in SWI: Association with Vascular Risk Factors, White Matter Hyperintensity Burden, and Cognitive Function.
AJNR. American journal of neuroradiology
May 2, 2025
BACKGROUND AND PURPOSE: The amount and distribution of cerebral microbleeds (CMB) are important risk factors for cognitive impairment. Our objective was to train and validate a deep learning (DL)-based segmentation model for cerebral microbleeds (CMB...
Associations among white matter microstructural changes and the development of emotional reactivity and regulation in infancy.
Molecular psychiatry
Apr 23, 2025
Deficits in emotional reactivity and regulation assessed in infancy, including high levels of negative emotionality (NE), low positive emotionality (PE) and low soothability, can predict future affective and behavioral disorders. White matter (WM) tr...
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