AIMC Topic: White Matter
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Predicting treatment response in individuals with major depressive disorder using structural MRI-based similarity features.
BMC psychiatry
May 26, 2025
BACKGROUND: Major Depressive Disorder (MDD) is a prevalent mental health condition with significant societal impact. Structural magnetic resonance imaging (sMRI) and machine learning have shown promise in psychiatry, offering insights into brain abno...
The value of radiomics features of white matter hyperintensities in diagnosing cognitive frailty: a study based on T2-FLAIR imaging.
BMC medical imaging
May 22, 2025
BACKGROUND: White matter hyperintensities (WMHs) are closely associated with cognitive frailty (CF). This study aims to explore the potential diagnostic value of WMHs for CF based on radiomics approaches, thereby providing a novel methodology for the...
Relevance of choroid plexus volumes in multiple sclerosis.
Fluids and barriers of the CNS
May 8, 2025
BACKGROUND: The choroid plexus (ChP) plays a pivotal role in inflammatory processes that occur in multiple sclerosis (MS). The enlargement of the ChP in relapsing-remitting multiple sclerosis (RRMS) is considered to be an indication of disease activi...
Automated Quantification of Cerebral Microbleeds in SWI: Association with Vascular Risk Factors, White Matter Hyperintensity Burden, and Cognitive Function.
AJNR. American journal of neuroradiology
May 2, 2025
BACKGROUND AND PURPOSE: The amount and distribution of cerebral microbleeds (CMB) are important risk factors for cognitive impairment. Our objective was to train and validate a deep learning (DL)-based segmentation model for cerebral microbleeds (CMB...
Associations among white matter microstructural changes and the development of emotional reactivity and regulation in infancy.
Molecular psychiatry
Apr 23, 2025
Deficits in emotional reactivity and regulation assessed in infancy, including high levels of negative emotionality (NE), low positive emotionality (PE) and low soothability, can predict future affective and behavioral disorders. White matter (WM) tr...
Uncertainty mapping and probabilistic tractography using Simulation-based Inference in diffusion MRI: A comparison with classical Bayes.
Medical image analysis
Apr 20, 2025
Simulation-Based Inference (SBI) has recently emerged as a powerful framework for Bayesian inference: Neural networks are trained on simulations from a forward model, and learn to rapidly estimate posterior distributions. We here present an SBI frame...
Machine learning prediction model for functional prognosis of acute ischemic stroke based on MRI radiomics of white matter hyperintensities.
BMC medical imaging
Mar 19, 2025
OBJECTIVE: The purpose of the current study is to explore the value of a nomogram that integrates clinical factors and MRI white matter hyperintensities (WMH) radiomics features in predicting the prognosis at 90 days for patients with acute ischemic ...
Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals.
Nature communications
Mar 19, 2025
Comorbid cardiovascular and metabolic risk factors (CVM) differentially impact brain structure and increase dementia risk, but their specific magnetic resonance imaging signatures (MRI) remain poorly characterized. To address this, we developed and v...
Dynamic glucose enhanced imaging using direct water saturation.
Magnetic resonance in medicine
Mar 17, 2025
PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based li...
A deep learning approach to multi-fiber parameter estimation and uncertainty quantification in diffusion MRI.
Medical image analysis
Mar 14, 2025
Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors such as va...
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