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White Matter

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Automatic Detection of Cognitive Impairment in Patients With White Matter Hyperintensity Using Deep Learning and Radiomics.

American journal of Alzheimer's disease and other dementias
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH p...

Enhanced U-Net for Infant Brain MRI Segmentation: A (2+1)D Convolutional Approach.

Sensors (Basel, Switzerland)
BACKGROUND: Infant brain tissue segmentation from MRI data is a critical task in medical imaging, particularly challenging due to the evolving nature of tissue contrasts in the early months of life. The difficulty increases as gray matter (GM) and wh...

A deep learning approach to multi-fiber parameter estimation and uncertainty quantification in diffusion MRI.

Medical image analysis
Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors such as va...

Machine learning prediction model for functional prognosis of acute ischemic stroke based on MRI radiomics of white matter hyperintensities.

BMC medical imaging
OBJECTIVE: The purpose of the current study is to explore the value of a nomogram that integrates clinical factors and MRI white matter hyperintensities (WMH) radiomics features in predicting the prognosis at 90 days for patients with acute ischemic ...

Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals.

Nature communications
Comorbid cardiovascular and metabolic risk factors (CVM) differentially impact brain structure and increase dementia risk, but their specific magnetic resonance imaging signatures (MRI) remain poorly characterized. To address this, we developed and v...

WMH-DualTasker: A Weakly Supervised Deep Learning Model for Automated White Matter Hyperintensities Segmentation and Visual Rating Prediction.

Human brain mapping
White matter hyperintensities (WMH) are neuroimaging markers linked to an elevated risk of cognitive decline. WMH severity is typically assessed via visual rating scales and through volumetric segmentation. While visual rating scales are commonly use...

TractCloud-FOV: Deep Learning-Based Robust Tractography Parcellation in Diffusion MRI With Incomplete Field of View.

Human brain mapping
Tractography parcellation classifies streamlines reconstructed from diffusion MRI into anatomically defined fiber tracts for clinical and research applications. However, clinical scans often have incomplete fields of view (FOV) where brain regions ar...

The Shape of the Brain's Connections Is Predictive of Cognitive Performance: An Explainable Machine Learning Study.

Human brain mapping
The shape of the brain's white matter connections is relatively unexplored in diffusion magnetic resonance imaging (dMRI) tractography analysis. While it is known that tract shape varies in populations and across the human lifespan, it is unknown if ...

Virtual white matter: a novel system for cross-dish neural interaction and modulation.

Journal of neural engineering
. Biological neural networks (BNNs) are characterized by complex interregional connectivity, allowing for seamless communication between different brain regions.models traditionally consist of single-dish neural cultures that cannot recapitulate the ...

Automated Whole-Brain Focal Cortical Dysplasia Detection Using MR Fingerprinting With Deep Learning.

Neurology
BACKGROUND AND OBJECTIVES: Focal cortical dysplasia (FCD) is a common pathology for pharmacoresistant focal epilepsy, yet detection of FCD on clinical MRI is challenging. Magnetic resonance fingerprinting (MRF) is a novel quantitative imaging techniq...