Deep learning-assisted differentiation of pathologically proven atypical and typical hepatocellular carcinoma (HCC) versus non-HCC on contrast-enhanced MRI of the liver.

Journal: European radiology
Published Date:

Abstract

OBJECTIVES: To train a deep learning model to differentiate between pathologically proven hepatocellular carcinoma (HCC) and non-HCC lesions including lesions with atypical imaging features on MRI.

Authors

  • Paula M Oestmann
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Clinton J Wang
    CSAIL/EECS, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Lynn J Savic
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Charlie A Hamm
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Sophie Stark
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Isabel Schobert
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Bernhard Gebauer
    Department of Diagnostic and Interventional Radiology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Todd Schlachter
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520.
  • MingDe Lin
    Philips Research North America, Cambridge, Massachusetts.
  • Jeffrey C Weinreb
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Ramesh Batra
    Department of Transplantation and Immunology, 333 Cedar Street, New Haven, CT, 06520, USA.
  • David Mulligan
    Department of Transplantation and Immunology, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Xuchen Zhang
    Department of Pathology, Yale School of Medicine, 310 Cedar Street, New Haven, CT, 06520, USA.
  • James S Duncan
    Biomedical Engineering, Yale University, New Haven, CT 06511, USA.
  • Julius Chapiro
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520. Electronic address: julius.chapiro@yale.edu.