Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
PMID: 33779561

Abstract

OBJECTIVE: The saline suppression test (SST) and captopril challenge test (CCT) are commonly used confirmatory tests for primary aldosteronism (PA). Seated SST (SSST) has been reported to be superior to recumbent SST. Whether SSST is better than CCT remains unclear. We aimed to compare the diagnostic accuracy of SSST and CCT in a prospective study.

Authors

  • Bin Liu
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Endocrinology, Neijiang First People's Hospital, Chongqing, China.
  • Jinbo Hu
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Ying Song
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Wenwen He
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Qingfeng Cheng
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhihong Wang
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhengping Feng
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhipeng Du
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhixin Xu
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Jun Yang
    Cardiovascular Endocrinology Laboratory, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Medicine, Monash University, Clayton, Victoria, Australia.
  • Qifu Li
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: liqifu@yeah.net.
  • Shumin Yang
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: 443068494@qq.com.

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