Proactive Construction of an Annotated Imaging Database for Artificial Intelligence Training.

Journal: Journal of digital imaging
Published Date:

Abstract

Artificial intelligence (AI) holds much promise for enabling highly desired imaging diagnostics improvements. One of the most limiting bottlenecks for the development of useful clinical-grade AI models is the lack of training data. One aspect is the large amount of cases needed and another is the necessity of high-quality ground truth annotation. The aim of the project was to establish and describe the construction of a database with substantial amounts of detail-annotated oncology imaging data from pathology and radiology. A specific objective was to be proactive, that is, to support undefined subsequent AI training across a wide range of tasks, such as detection, quantification, segmentation, and classification, which puts particular focus on the quality and generality of the annotations. The main outcome of this project was the database as such, with a collection of labeled image data from breast, ovary, skin, colon, skeleton, and liver. In addition, this effort also served as an exploration of best practices for further scalability of high-quality image collections, and a main contribution of the study was generic lessons learned regarding how to successfully organize efforts to construct medical imaging databases for AI training, summarized as eight guiding principles covering team, process, and execution aspects.

Authors

  • Caroline Bivik Stadler
    Center for Medical Image Science and Visualization (CMIV), Linköping University Hospital, Linköping University, SE-581 85, Linköping, Sweden. caroline.bivik.stadler@liu.se.
  • Martin Lindvall
    Sectra AB, Teknikringen 20, SE-583 30, Linköping, Sweden.
  • Claes Lundström
    Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.
  • Anna Bodén
    Center for Medical Image Science and Visualization (CMIV), Linköping University Hospital, Linköping University, SE-581 85, Linköping, Sweden.
  • Karin Lindman
    Center for Medical Image Science and Visualization (CMIV), Linköping University Hospital, Linköping University, SE-581 85, Linköping, Sweden.
  • Jeronimo Rose
    Center for Medical Image Science and Visualization (CMIV), Linköping University Hospital, Linköping University, SE-581 85, Linköping, Sweden.
  • Darren Treanor
    Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Johan Blomma
    Department of Radiology, Region Östergötland, Linköping University Hospital, SE-581 85, Linköping, Sweden.
  • Karin Stacke
    Sectra AB, Teknikringen 20, SE-583 30, Linköping, Sweden.
  • Nicolas Pinchaud
    ContextVision AB, Klara Norra Kyrkogata 31, SE-111 22, Stockholm, Sweden.
  • Martin Hedlund
    ContextVision AB, Linköping, Sweden.
  • Filip Landgren
    Department of Radiology, Region Östergötland, Linköping University Hospital, SE-581 85, Linköping, Sweden.
  • Mischa Woisetschläger
    Department of Radiology and Department of Medical and Health Sciences, Linköping.
  • Daniel Forsberg
    Sectra, Teknikringen 20, 583 30, Linköping, SE, Sweden. daniel.forsberg@sectra.com.