Artefact Detection in Impedance Pneumography Signals: A Machine Learning Approach.

Journal: Sensors (Basel, Switzerland)
Published Date:

Abstract

Impedance pneumography has been suggested as an ambulatory technique for the monitoring of respiratory diseases. However, its ambulatory nature makes the recordings more prone to noise sources. It is important that such noisy segments are identified and removed, since they could have a huge impact on the performance of data-driven decision support tools. In this study, we investigated the added value of machine learning algorithms to separate clean from noisy bio-impedance signals. We compared three approaches: a heuristic algorithm, a feature-based classification model (SVM) and a convolutional neural network (CNN). The dataset consists of 47 chronic obstructive pulmonary disease patients who performed an inspiratory threshold loading protocol. During this protocol, their respiration was recorded with a bio-impedance device and a spirometer, which served as a gold standard. Four annotators scored the signals for the presence of artefacts, based on the reference signal. We have shown that the accuracy of both machine learning approaches (SVM: 87.77 ± 2.64% and CNN: 87.20 ± 2.78%) is significantly higher, compared to the heuristic approach (84.69 ± 2.32%). Moreover, no significant differences could be observed between the two machine learning approaches. The feature-based and neural network model obtained a respective AUC of 92.77±2.95% and 92.51±1.74%. These findings show that a data-driven approach could be beneficial for the task of artefact detection in respiratory thoracic bio-impedance signals.

Authors

  • Jonathan Moeyersons
    STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Department of Electrical Engineering (ESAT), KU Leuven, 3001 Leuven, Belgium.
  • John Morales
    STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Department of Electrical Engineering (ESAT), KU Leuven, 3001 Leuven, Belgium.
  • Nick Seeuws
    STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Department of Electrical Engineering (ESAT), KU Leuven, 3001 Leuven, Belgium.
  • Chris Van Hoof
    IMEC Leuven, Kapeldreef 75, 3001 Heverlee, Belgium; Stichting IMEC Nederland, High Tech Campus 31, Eindhoven 5656 AE, The Netherlands.
  • Evelien Hermeling
    Imec the Netherlands/Holst Centre, 5600 Eindhoven, The Netherlands.
  • Willemijn Groenendaal
    Stichting IMEC Nederland, High Tech Campus 31, Eindhoven 5656 AE, The Netherlands.
  • Rik Willems
    KU Leuven, Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Leuven, Belgium; UZ Leuven, Leuven, Belgium. Electronic address: rik.willems@kuleuven.be.
  • Sabine Van Huffel
    Katholieke Universiteit Leuven.
  • Carolina Varon
    Department of Electrical Engineering-ESAT, STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics and iMinds Medical IT Department, KU Leuven, Leuven, Belgium.