Applying deep learning in digital breast tomosynthesis for automatic breast cancer detection: A review.

Journal: Medical image analysis
Published Date:

Abstract

The relatively recent reintroduction of deep learning has been a revolutionary force in the interpretation of diagnostic imaging studies. However, the technology used to acquire those images is undergoing a revolution itself at the very same time. Digital breast tomosynthesis (DBT) is one such technology, which has transformed the field of breast imaging. DBT, a form of three-dimensional mammography, is rapidly replacing the traditional two-dimensional mammograms. These parallel developments in both the acquisition and interpretation of breast images present a unique case study in how modern AI systems can be designed to adapt to new imaging methods. They also present a unique opportunity for co-development of both technologies that can better improve the validity of results and patient outcomes. In this review, we explore the ways in which deep learning can be best integrated into breast cancer screening workflows using DBT. We first explain the principles behind DBT itself and why it has become the gold standard in breast screening. We then survey the foundations of deep learning methods in diagnostic imaging, and review the current state of research into AI-based DBT interpretation. Finally, we present some of the limitations of integrating AI into clinical practice and the opportunities these present in this burgeoning field.

Authors

  • Jun Bai
    Department of Hematology, Gansu Provincial Key Laboratory of Hematology , Lanzhou University Second Hospital , Lanzhou 730000 , China.
  • Russell Posner
    University of Connecticut School of Medicine, 263 Farmington Ave. Farmington, CT 06030, USA.
  • Tianyu Wang
    State Key Laboratory of Mechanical System and Vibration, Shanghai Jiao Tong University; University of Michigan-Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University.
  • Clifford Yang
    Department of Diagnostic Imaging, University of Connecticut Health Center, Farmington, 06030, CT, USA.
  • Sheida Nabavi
    Department of Computer Science and Engineering, University of Connecticut, Storrs, 06269, CT, USA.