Eye-color and Type-2 diabetes phenotype prediction from genotype data using deep learning methods.

Journal: BMC bioinformatics
PMID:

Abstract

BACKGROUND: Genotype-phenotype predictions are of great importance in genetics. These predictions can help to find genetic mutations causing variations in human beings. There are many approaches for finding the association which can be broadly categorized into two classes, statistical techniques, and machine learning. Statistical techniques are good for finding the actual SNPs causing variation where Machine Learning techniques are good where we just want to classify the people into different categories. In this article, we examined the Eye-color and Type-2 diabetes phenotype. The proposed technique is a hybrid approach consisting of some parts from statistical techniques and remaining from Machine learning.

Authors

  • Muhammad Muneeb
    Department of Electrical Engineering and Computer Science, Center for Biotechnology Khalifa University, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
  • Andreas Henschel
    Department of Electrical Engineering and Computer Science, Center for Biotechnology Khalifa University, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates. andreas.henschel@ku.ac.ae.