AIMC Topic: Phenotype
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LC-MS/MS metabolomics unravels the resistant phenotype of carbapenemase-producing Enterobacterales.
Metabolomics : Official journal of the Metabolomic Society
Aug 12, 2025
INTRODUCTION: The degree of antimicrobial resistance demonstrated by carbapenemase-producing Enterobacterales (CPE) represents a growing public health challenge. Conventional methods for detecting CPE involve culture-based techniques with lengthy inc...
Machine learning models for predicting morphological traits and optimizing genotype and planting date in roselle (Hibiscus Sabdariffa L.).
Scientific reports
Aug 9, 2025
Accurate prediction and optimization of morphological traits in Roselle are essential for enhancing crop productivity and adaptability to diverse environments. In the present study, a machine learning framework was developed using Random Forest and M...
Integrated phenotypic analysis, predictive modeling, and identification of novel trait-associated loci in a diverse Theobroma cacao collection.
BMC plant biology
Aug 9, 2025
BACKGROUND: Cacao (Theobroma cacao L.) breeding and improvement rely on understanding germplasm diversity and trait architecture. This study characterized a cacao collection (173 accessions) evaluated in Puerto Rico, examining phenotypic diversity, t...
Phenotype augmentation using generative AI for isocitrate dehydrogenase mutation prediction in glioma.
Scientific reports
Aug 7, 2025
This study investigated the effects of feature augmentation, which uses generated images with specific imaging features, on the performance of isocitrate dehydrogenase (IDH) mutation prediction models in gliomas. A total of 598 patients were included...
AdaptiveGS: an explainable genomic selection framework based on adaptive stacking ensemble machine learning.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Aug 7, 2025
We developed an adaptive and unified stacking genomic selection framework and designed a model interpretation strategy to identify the candidate significant SNPs of target traits. Genomic selection (GS) is an important technique in modern molecular b...
Developing a Behavioral Phenotyping Layer for Artificial Intelligence-Driven Predictive Analytics in a Digital Resiliency Course: Protocol for a Randomized Controlled Trial.
JMIR research protocols
Aug 6, 2025
BACKGROUND: Digital interventions for mental health are pivotal for addressing barriers such as stigma, cost, and accessibility, particularly for underserved populations. While the effectiveness of digital interventions has been established, poor adh...
In silico prediction of variant effects: promises and limitations for precision plant breeding.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Jul 28, 2025
Sequence-based AI models show great potential for prediction of variant effects at high resolution, but their practical value in plant breeding remains to be confirmed through rigorous validation studies. Plant breeding has traditionally relied on ph...
Interpretable machine learning-guided single-cell mapping deciphers multi-lineage pancreatic dysregulation in type 2 diabetes.
Cardiovascular diabetology
Jul 24, 2025
BACKGROUND: Pancreatic cellular heterogeneity is fundamental to systemic metabolic regulation, yet its pathological remodeling in diabetes remains poorly characterized.
Advances in machine learning for ABCA4-related retinopathy: segmentation and phenotyping.
International ophthalmology
Jul 23, 2025
PURPOSE: Stargardt disease, also called ABCA4-related retinopathy (ABCA4R), is the most common form of juvenile-onset macular dystrophy and yet lacks an FDA approved treatment. Substantial progress has been made through landmark studies like that of ...
Extensive novel diversity and phenotypic associations in the dromedary camel microbiome are revealed through deep metagenomics and machine learning.
PloS one
Jul 17, 2025
The dromedary camel, also known as one-humped camel or Arabian camel, is iconic and economically important to Arabian society. Its contemporary importance in commerce and transportation, along with the historical and modern use of its milk and meat p...
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