Abdominal multi-organ segmentation with cascaded convolutional and adversarial deep networks.

Journal: Artificial intelligence in medicine
Published Date:

Abstract

Abdominal anatomy segmentation is crucial for numerous applications from computer-assisted diagnosis to image-guided surgery. In this context, we address fully-automated multi-organ segmentation from abdominal CT and MR images using deep learning. The proposed model extends standard conditional generative adversarial networks. Additionally to the discriminator which enforces the model to create realistic organ delineations, it embeds cascaded partially pre-trained convolutional encoder-decoders as generator. Encoder fine-tuning from a large amount of non-medical images alleviates data scarcity limitations. The network is trained end-to-end to benefit from simultaneous multi-level segmentation refinements using auto-context. Employed for healthy liver, kidneys and spleen segmentation, our pipeline provides promising results by outperforming state-of-the-art encoder-decoder schemes. Followed for the Combined Healthy Abdominal Organ Segmentation (CHAOS) challenge organized in conjunction with the IEEE International Symposium on Biomedical Imaging 2019, it gave us the first rank for three competition categories: liver CT, liver MR and multi-organ MR segmentation. Combining cascaded convolutional and adversarial networks strengthens the ability of deep learning pipelines to automatically delineate multiple abdominal organs, with good generalization capability. The comprehensive evaluation provided suggests that better guidance could be achieved to help clinicians in abdominal image interpretation and clinical decision making.

Authors

  • Pierre-Henri Conze
    Inserm, UMR 1101, Brest F-29200, France; Institut Mines-Télécom Atlantique, Brest F-29200, France.
  • Ali Emre Kavur
    Dokuz Eylul University, Cumhuriyet Bulvarı, 35210 Izmir, Turkey.
  • Emilie Cornec-Le Gall
    University Brest, Inserm, UMR 1078, GGB, CHU Brest, F-29200 Brest, France.
  • Naciye Sinem Gezer
    Department of Radiology, Dokuz Eylül University School of Medicine, İzmir, Turkey.
  • Yannick Le Meur
    University Brest, Inserm, UMR 1227, LBAI, CHU Brest, F-29200 Brest, France.
  • M Alper Selver
    Department of Electrical and Electronics Engineering, Dokuz Eylül University, İzmir, Turkey.
  • François Rousseau
    Laboratory of medical information processing - LaTIM, Inserm UMR 1101, CS 93837, Université de Bretagne Occidentale, 22, avenue Camille-Desmoulins, 29238 Brest cedex 3, France; IMT Atlantique, LaTIM, UMR Inserm 1101, 655, avenue du Technopole, 29200 Plouzané, France.